Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138671 | 0.80 | FFAR1 (0.49) | CNR2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL28214912 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CNR2CNR1LMNAHDAC3 | |
| SCHEMBL29042236 | 0.74 | LMNA (0.57) | CNR2CNR1LMNAKDM4EDUSP3 | |
| SCHEMBL7592305 | 0.73 | — | — | |
| SCHEMBL29073212 | 0.73 | LMNA (0.59) | CNR2CNR1LMNAKDM4EDUSP3 | |
| SCHEMBL5944386 | 0.73 | LMNA (0.59) | CNR2CNR1LMNAKDM4EDUSP3 | |
| SCHEMBL29073348 | 0.73 | LMNA (0.59) | CNR2CNR1LMNAKDM4EDUSP3 | |
| SCHEMBL29138692 | 0.73 | FFAR4 (0.49) | CNR2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL29138675 | 0.73 | FFAR4 (0.49) | CNR2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL11407664 | 0.71 | ALDH1A1 (0.50) | ALDH1A1CNR2CNR1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011158176-A2 | GOLD COMPLEXES | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2011-12-22 | — | — | WO | claimed |