SCHEMBL28214912

SCHEMBL28214912

CCCC(=O)ONCC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
EPHX1 P07099 1/20 0.39
CA12 O43570 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
CNR2 P34972 2/20 0.36
LMNA P02545 3/20 0.34
CNR1 P21554 1/20 0.34
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
ALOX15 P16050 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MMP1 P03956 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28677914 0.85 LMNA (0.55) ALDH1A1EPHX1CNR2LMNACNR1
SCHEMBL9998983 0.79 ALDH1A1 (0.45) ALDH1A1CNR2LMNACNR1HDAC3
SCHEMBL2778489 0.79 ADH1B (0.39) ALDH1A1CA12CA7CA9CA14
SCHEMBL27762872 0.78 MMP1 (0.41) ALDH1A1EPHX1CA12CA7CA9
SCHEMBL3833564 0.78 CNR2 (0.57) CYP2C19CNR2LMNACNR1ALOX15
SCHEMBL7592305 0.78
SCHEMBL28428290 0.77 CNR2 (0.68) CYP2C19CNR2LMNACNR1ALOX15
Ammonia Solution, Strong SCHEMBL27695584 0.77 MMP1 (0.39) ALDH1A1EPHX1CA12CA7CA9
SCHEMBL11407664 0.76 ALDH1A1 (0.50) ALDH1A1EPHX1CA12CA14CNR2
SCHEMBL27492429 0.75 CYP2D6 (0.44) ALDH1A1EPHX1CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107987196-A For catalyst constituent for olefinic polymerization and its catalyst 中国石油化工股份有限公司 2018-05-04 CN claimed
CN-107987189-A A kind of catalyst component for olefin and its preparation method and application 中国石油化工股份有限公司 2018-05-04 CN claimed
CN-109890852-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-10-20 CN disclosed
CN-107987196-A For catalyst constituent for olefinic polymerization and its catalyst 中国石油化工股份有限公司 2018-05-04 CN disclosed