SCHEMBL999925

SCHEMBL999925

Nc1ccc(C(=O)O)c(N)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.52
KMT2A Q03164 5/20 0.52
GFER P55789 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
MAPT P10636 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 4/20 0.50
THRB P10828 4/20 0.50
RECQL P46063 3/20 0.50
CASP6 P55212 2/20 0.50
POLB P06746 2/20 0.50
CASP7 P55210 2/20 0.50
USP2 O75604 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50
BLM P54132 1/20 0.50
MCL1 Q07820 1/20 0.50
G6PD P11413 1/20 0.50
GLA P06280 1/20 0.48
KEAP1 Q14145 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792992 0.89 CASP7 (0.58) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL690406 0.89 CASP7 (0.58) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL1162152 0.81 MMP2 (0.57) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL1352295 0.81 KDM4E (0.48) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL2949804 0.81 MMP2 (0.57) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL8761666 0.80 IKBKB (0.44) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL29443033 0.79 CYP3A4 (0.48) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL22905001 0.79 CYP3A4 (0.48) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL2926609 0.79 KDM4E (0.48) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL555823 0.79 KDM4E (0.48) KDM4EKMT2AGFERRXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283505-A Method for synthesizing phloroglucinol from tri-acetylated triaminobenzoic acid 北京理工大学 2023-06-23 CN claimed
US-20120168370-A1 METHOD OF IMPROVING REJECTION OF PERMEABLE MEMBRANE AND PERMEABLE MEMBRANE KURITA WATER INDUSTRIES LTD. (JP) 2012-07-05 US claimed
CN-120019749-A Spraying bias flow aid 禾大国际股份公开有限公司 2025-05-20 CN disclosed
CN-117903431-A Carbon nano tube composite material and preparation method and application thereof 浙江王点科技有限公司 2024-04-19 CN disclosed
CN-117487634-A Cleaning composition for semiconductor, method for preparing the same and method for cleaning semiconductor 长沙艾森设备维护技术有限公司 2024-02-02 CN disclosed
CN-115155322-B Polyamide reverse osmosis membrane online repairing agent and preparation and repairing methods thereof 鞍钢栗田(鞍山)水处理有限公司 2024-01-30 CN disclosed
WO-2024000743-A1 ANTI-ULTRAVIOLET SUPER-HYDROPHOBIC FABRIC AND PREPARATION METHOD THEREFOR 苏州大学 2024-01-04 WO disclosed
CN-115490597-B Synthetic method of fluorotoluene derivative 西安近代化学研究所 2023-10-20 CN disclosed
CN-114990885-B Ultraviolet-resistant superhydrophobic fabric and preparation method thereof 苏州大学 2023-08-15 CN disclosed
CN-116283505-A Method for synthesizing phloroglucinol from tri-acetylated triaminobenzoic acid 北京理工大学 2023-06-23 CN disclosed
CN-116283505-A Method for synthesizing phloroglucinol from tri-acetylated triaminobenzoic acid 北京理工大学 2023-06-23 CN disclosed
EP-0744970-A1 IMPROVED PROCESS FOR FIXATION OF CALCIFICATION-RESISTANT BIOLOGICAL TISSUE BIOMEDICAL DESIGN, INC. (US) 1996-12-04 EP disclosed
WO-1995022361-A1 IMPROVED PROCESS FOR FIXATION OF CALCIFICATION-RESISTANT BIOLOGICAL TISSUE BIOMEDICAL DESIGN, INC. (US) 1995-08-24 WO disclosed
WO-1993012211-A1 LUBRICATING OIL CONTAINING ASHLESS NON-PHOSPHORUS ADDITIVE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-06-24 WO disclosed
US-5108462-A Amine salt and-or amide of (thio)benzoic acid derivative EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-28 US disclosed
US-5076945-A Hydrocarbyl substituted amine salts of acid or dithioacid EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-12-31 US disclosed
US-4569776-A A MIXTURE OF AN ELECTRON-WITHDRAWING AROMATIC CARBOXYLIC ACID AND AN ELECTRON-RELEASING AROMATIC CARBOXYLIC ACID; LUBRICANTS OLIN CORPORATION (US) 1986-02-11 US disclosed
US-3985797-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3985796-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3931295-A Hydroxylation of aromatic compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-01-06 US disclosed