Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936887 | 0.85 | AGBL2 (0.52) | AGBL2GAAALDH1A1MAPTPOLQ | |
| SCHEMBL3932258 | 0.84 | MAPT (0.56) | AGBL2GAAALDH1A1MAPTCYP1A2 | |
| SCHEMBL3924887 | 0.83 | AGBL2 (0.55) | AGBL2GAAALDH1A1MAPTCYP1A2 | |
| SCHEMBL3935935 | 0.83 | AGBL2 (0.51) | AGBL2GAAALDH1A1MAPTPOLQ | |
| SCHEMBL12698841 | 0.81 | AGBL2 (1.00) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3928786 | 0.80 | PTGDR2 (0.48) | AGBL2CYP2C19POLQFFAR1FFAR4 | |
| SCHEMBL3930078 | 0.79 | PTGDR2 (0.50) | AGBL2GAAALDH1A1MAPTFFAR1 | |
| SCHEMBL3939229 | 0.79 | AGBL2 (0.43) | AGBL2FFAR1NPSR1 | |
| Cyclopropane SCHEMBL11659767 | 0.78 | EGLN1 (0.48) | AGBL2FFAR1FFAR4RXRARXRB | |
| SCHEMBL5717719 | 0.75 | MAPT (0.58) | AGBL2GAAALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |