VPS28

Vacuolar protein sorting-associated protein 28 homolog · Q9UK41 · VPS28 on Sugi Atlas →

0 patent compounds predicted against VPS28, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to VPS28 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C PHASE1/PHASE2COMPLETED
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients PHASE2COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction EARLY_PHASE1RECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Natural History Study of Patients With VCP-related Disease nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Autophagy Bladder Cancer nanUNKNOWN
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank nanCOMPLETED
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients nanRECRUITING
Fasting, Exercise, and Diet to Activate Autophagy in Depression nanNOT_YET_RECRUITING
Time Course for Fasting-induced Autophagy in Humans nanWITHDRAWN
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Study of Neurodegenerative Diseases Induced Stem Cells in Patients and Healthy Family Controls. nanUNKNOWN
Clinical and Genetic Studies of VACTERL Association nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a VPS28 binder may also engage these)

ProteinNameSimilarity
B5DEN9 1.000 B5DEN9 →
Q9D1C8 1.000 Q9D1C8 →
Q3T178 1.000 Q3T178 →
Q7Z3J2 0.961 Q7Z3J2 →
Q5R8N4 0.960 Q5R8N4 →
AP2A1 AP-2 complex subunit alpha-1 0.959 landscape →
RPTOR Regulatory-associated protein of mTOR 0.958 landscape →
AP2A2 AP-2 complex subunit alpha-2 0.958 landscape →
Q1RLU8 0.958 Q1RLU8 →
Q2PG42 0.958 Q2PG42 →
Q5R5F8 0.958 Q5R5F8 →
Q2IBD0 0.958 Q2IBD0 →
Q8K4Q0 0.958 Q8K4Q0 →
Q9NVE7 0.956 Q9NVE7 →
Q4R4U1 0.955 Q4R4U1 →
P17426 0.955 P17426 →
Q9Y4J8 0.955 Q9Y4J8 →
A0M8U1 0.954 A0M8U1 →
Q8L5Y9 0.954 Q8L5Y9 →
Q99M96 0.954 Q99M96 →
Q8VCX5 0.953 Q8VCX5 →
Q9BPX6 0.953 Q9BPX6 →
A9JRA0 0.953 A9JRA0 →
B1H2N3 0.952 B1H2N3 →
GPS1 COP9 signalosome complex subunit 1 0.952 landscape →
P17427 0.952 P17427 →
Q9TUM3 0.952 Q9TUM3 →
Q5ZLA5 0.952 Q5ZLA5 →
Q62771 0.952 Q62771 →
Q9TUZ0 0.952 Q9TUZ0 →