Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 7/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | EHD1 | Q9H4M9 | 5/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24625883 | 1.00 | HDAC4 (0.52) | HDAC4KEAP1EHD1TCF4CTNNB1 | |
| SCHEMBL24625885 | 1.00 | HDAC4 (0.52) | HDAC4KEAP1EHD1TCF4CTNNB1 | |
| SCHEMBL24627059 | 0.79 | EHD1 (0.54) | HDAC4EHD1MMP2OPRM1OPRD1 | |
| SCHEMBL24626991 | 0.75 | EHD1 (0.58) | HDAC4EHD1TCF4CTNNB1MMP2 | |
| SCHEMBL26935056 | 0.74 | ITGB3 (0.61) | HDAC4KEAP1HDAC1HDAC3HDAC7 | |
| SCHEMBL24627335 | 0.74 | EHD1 (0.53) | HDAC4EHD1TCF4CTNNB1MMP2 | |
| SCHEMBL26935060 | 0.73 | HDAC3 (0.66) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL25937942 | 0.72 | OPRM1 (0.53) | HDAC4MMP2OPRM1OPRD1HDAC1 | |
| SCHEMBL29602298 | 0.71 | HDAC4 (0.59) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL29779766 | 0.71 | KEAP1 (0.55) | HDAC4KEAP1TCF4CTNNB1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148851-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2022-07-14 | — | — | WO | disclosed |