EIF4B

Eukaryotic translation initiation factor 4B · P23588 · EIF4B on Sugi Atlas →

0 patent compounds predicted against EIF4B, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF4B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit PHASE2/PHASE3WITHDRAWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis PHASE1/PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors PHASE1ACTIVE_NOT_RECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
MEHMO Natural History and Biomarkers nanRECRUITING
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Detection of MicroRNA-25 in the Diagnosis of Pancreatic Cancer nanUNKNOWN
Research on the Early and Prognosis Diagnosis of Vascular Dementia nanRECRUITING
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EIF4B binder may also engage these)

ProteinNameSimilarity
Q8BGD9 1.000 Q8BGD9 →
G3BP2 Ras GTPase-activating protein-binding protein 2 0.963 landscape →
Q5R9L3 0.961 Q5R9L3 →
P97379 0.957 P97379 →
Q32LC7 0.956 Q32LC7 →
G3BP1 Ras GTPase-activating protein-binding protein 1 0.955 landscape →
P97855 0.955 P97855 →
SAP30BP SAP30-binding protein 0.953 landscape →
Q5RB87 0.952 Q5RB87 →
B2GV05 0.952 B2GV05 →
Q91YE7 0.951 Q91YE7 →
HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0.951 landscape →
Q9WU01 0.951 Q9WU01 →
Q1RMU5 0.951 Q1RMU5 →
Q9P2N5 0.950 Q9P2N5 →
P52756 0.950 P52756 →
KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 0.950 landscape →
Q66II8 0.949 Q66II8 →
Q5SFM8 0.949 Q5SFM8 →
O95232 0.949 O95232 →
LUC7L2 Putative RNA-binding protein Luc7-like 2 0.947 landscape →
YTHDF2 YTH domain-containing family protein 2 0.947 landscape →
Q8UUW7 0.947 Q8UUW7 →
Q9Z1M8 0.946 Q9Z1M8 →
Q920F3 0.946 Q920F3 →
Q9Z204 0.946 Q9Z204 →
YTHDF1 YTH domain-containing family protein 1 0.946 landscape →
Q4R5D9 0.946 Q4R5D9 →
Q91YT7 0.946 Q91YT7 →
Q5NVI3 0.946 Q5NVI3 →