Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 18/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | ELOVL3 | Q9HB03 | 6/20 | 0.93 |
| ▸ | MAPT | P10636 | 1/20 | 0.93 |
| ▸ | HTT | P42858 | 1/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486655 | 0.96 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486253 | 0.95 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486064 | 0.95 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486256 | 0.95 | ELOVL6 (0.91) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486406 | 0.95 | ELOVL6 (0.91) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486337 | 0.95 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486551 | 0.95 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486069 | 0.94 | ELOVL6 (0.88) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486198 | 0.94 | ELOVL6 (0.88) | ELOVL6MEN1KMT2AELOVL3MAPT | |
| SCHEMBL486548 | 0.94 | ELOVL6 (1.00) | ELOVL6MEN1KMT2AELOVL3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | claimed |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | MSD K.K. (JP) | 2010-03-04 | — | — | US | claimed |
| EP-2145884-A1 | INDOLEDIONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-01-20 | — | — | EP | claimed |
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | WAVEBREAK INC (US) | 2024-06-27 | — | — | US | disclosed |
| WO-2022212568-A9 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022212568-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2022-10-06 | — | — | WO | disclosed |
| US-20160271137-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | UNIV PRINCETON (US) | 2016-09-22 | — | — | US | disclosed |
| US-9168269-B2 | Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150139949-A1 | ANTI-VIRAL COMBINATION THERAPY | KOYUNCU EMRE (US) | 2015-05-21 | — | — | US | disclosed |
| EP-2145884-B1 | INDOLEDIONE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130190381-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2013029006-A1 | DENGUE VIRUS AND YELLOW FEVER VIRUS THERAPIES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012139028-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | disclosed |
| WO-2011103516-A2 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2011-08-25 | — | — | WO | disclosed |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | MSD K.K. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2145884-A1 | INDOLEDIONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | LIPE, IDO1, ADRA1A | ELOVL6 1113/4885MEN1 2086/4885KMT2A 776/4885 |
| US-20160271137-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | FASN, PLIN1, PLIN3 | ELOVL6 18/4885MEN1 4760/4885KMT2A 2385/4885 |
| US-20130190381-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | FASN, PLIN1, PLIN3 | ELOVL6 18/4885MEN1 4760/4885KMT2A 2385/4885 |
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | CPT2, PC, SREBF2 | ELOVL6 48/4885MEN1 4713/4885KMT2A 4386/4885 |
| US-20150139949-A1 | ANTI-VIRAL COMBINATION THERAPY | HAVCR2, MAVS, ZC3HAV1 | ELOVL6 876/4885MEN1 4738/4885KMT2A 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.