GPAA1

GPI-anchor transamidase component GPAA1 · O43292 · GPAA1 on Sugi Atlas →

0 patent compounds predicted against GPAA1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GPAA1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis PHASE3RECRUITING
An Efficacy and Safety Study of AVR-RD-02 Compared to Enzyme Replacement Therapy for Treatment of Gaucher Disease Type 3 PHASE2/PHASE3WITHDRAWN
Ambroxol as a Treatment for Parkinson's Disease Dementia PHASE2UNKNOWN
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Natural History of Granulomatosis With Polyangiitis: Clinical and Genetic Biomarkers of Airway Disease NoAAC PR-03 Study nanWITHDRAWN
A Study Measuring Substances Potentially Indicating Bone Problems in Adults With Type 1 Gaucher Condition nanCOMPLETED
Registry Gangliosidoses nanUNKNOWN
Fibrosis, Inflammation, Oxygenation of Renal Tissue In FabrY Disease nanRECRUITING
Early Detection and Follow-Up of Patients With Fabry's Disease nanUNKNOWN
A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gaucher Disease nanCOMPLETED
GNAO1 Natural History Study nanUNKNOWN
Biomarker for Patients With Fabry Disease (BioFabry) nanWITHDRAWN
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Biomarker Analysis for GBA Associated Parkinson's Disease nanUNKNOWN
Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener's) and Microscopic Polyangiitis nanCOMPLETED
Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders nanRECRUITING
Chinese PD-GBA Registry nanRECRUITING
Omics Gaucher Study: Multiomic Approach nanACTIVE_NOT_RECRUITING
The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH) nanCOMPLETED
Biomarker for Gangliosidosis: BioGM1/BioGM2 (BioGM1/GM2) nanWITHDRAWN
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS) nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Immune Biomarkers Related to Bone Pathology in Patients With Type 1 Gaucher Disease nanUNKNOWN
Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Characterization of the Patient Population With Galactosialidosis nanCOMPLETED
Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GPAA1 binder may also engage these)

ProteinNameSimilarity
Q9WTK3 1.000 Q9WTK3 →
Q9UP52 0.973 Q9UP52 →
Q8VCM8 0.973 Q8VCM8 →
Q0V8G3 0.972 Q0V8G3 →
Q9JKX3 0.971 Q9JKX3 →
Q6NZ07 0.971 Q6NZ07 →
B2GUY2 0.971 B2GUY2 →
NCLN BOS complex subunit NCLN 0.971 landscape →
Q5R6S0 0.970 Q5R6S0 →
Q5XIA1 0.970 Q5XIA1 →
ABHD16A Phosphatidylserine lipase ABHD16A 0.970 landscape →
Q9HCN3 0.969 Q9HCN3 →
Q9Z1Q2 0.969 Q9Z1Q2 →
O89109 0.968 O89109 →
Q9BU23 0.968 Q9BU23 →
TRPM4 Transient receptor potential cation channel subfamily M member 4 0.967 landscape →
A0A8I3NGV2 0.967 A0A8I3NGV2 →
Q8BH73 0.967 Q8BH73 →
Q1JPD2 0.966 Q1JPD2 →
Q4R942 0.966 Q4R942 →
P70295 0.966 P70295 →
SOAT2 Sterol O-acyltransferase 2 0.966 landscape →
Q5ZKZ9 0.965 Q5ZKZ9 →
QPCTL Glutaminyl-peptide cyclotransferase-like protein 0.965 landscape →
Q00973 0.965 Q00973 →
O60683 0.965 O60683 →
Q6MG55 0.965 Q6MG55 →
Q8C3X8 0.964 Q8C3X8 →
Q16586 0.964 Q16586 →
Q4R8P0 0.964 Q4R8P0 →