IGF2BP3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL21943538	0.59	1/20
SCHEMBL21943762	0.57	1/20
SCHEMBL21944043	0.55	1/20
SCHEMBL21943004	0.55	1/20
SCHEMBL21942995	0.53	1/20
SCHEMBL21943411	0.53	1/20
SCHEMBL14042267	0.52	1/20
SCHEMBL21943429	0.52	1/20
SCHEMBL22066328	0.51	1/20
SCHEMBL21943540	0.49	1/20
SCHEMBL21943537	0.45	1/20
SCHEMBL24016281	0.44	1/20
SCHEMBL24532074	0.42	1/20
SCHEMBL1454562	0.42	1/20
SCHEMBL17612956	0.42	1/20
SCHEMBL12399198	0.42	1/20
SCHEMBL29911712	0.40	1/20

Clinical trials — most relevant to IGF2BP3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer	PHASE4	WITHDRAWN
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis	PHASE4	COMPLETED
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer	PHASE2	COMPLETED
Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors	PHASE2	COMPLETED
MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer	PHASE1/PHASE2	COMPLETED
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate	PHASE1	COMPLETED
Pappalysin 2 (PAPP-A2) Enzyme Replacement	PHASE1	COMPLETED
AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma	PHASE1	COMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer	nan	COMPLETED
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer	nan	UNKNOWN
Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt	nan	NOT_YET_RECRUITING
The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2)	nan	COMPLETED
Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation	nan	UNKNOWN
IGF and Other Neurotrophic Factors in Patients With Dementia	nan	COMPLETED
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention	nan	ACTIVE_NOT_RECRUITING
Molecular Quantification of Insulin mRNA	nan	COMPLETED
Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer	nan	COMPLETED
Adipocytokines in Endometrial Cancer	nan	COMPLETED
To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK	nan	COMPLETED
Role of LncRNA H19 in The Regulation of IGF-1R Expression	nan	COMPLETED
Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Effect of AT-derived miRNA on the Biology and Insulin Sensitivity of Skeletal Muscle in Humans	nan	COMPLETED
Epigenetics of Muscle Insulin Resistance	nan	COMPLETED
Biomarkers Related to Bone in Pediatric Gaucher Disease	nan	UNKNOWN
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer	nan	COMPLETED
Impact of Comprehensive Intervention on the Cardiometabolic Risk in Children With Central Obesity (IGENOI)Obesity	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Zinc and the Synthesis of Zinc Binding Proteins (Protocol B)	nan	COMPLETED
Epigenetics and the Origin of Muscle Insulin Resistance in Humans	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a IGF2BP3 binder may also engage these)

Protein	Name	Similarity
Q5ZLP8	—	1.000	Q5ZLP8 →
O42254	—	1.000	O42254 →
O73932	—	1.000	O73932 →
Q08CK7	—	1.000	Q08CK7 →
Q9PW80	—	1.000	Q9PW80 →
Q9CPN8	—	1.000	Q9CPN8 →
IGF2BP2	Insulin-like growth factor 2 mRNA-binding protein 2	1.000	landscape →
Q8CGX0	—	1.000	Q8CGX0 →
O57526	—	1.000	O57526 →
O88477	—	1.000	O88477 →
Q5SF07	—	1.000	Q5SF07 →
Q5RB68	—	1.000	Q5RB68 →
IGF2BP1	Insulin-like growth factor 2 mRNA-binding protein 1	0.998	landscape →
Q9Z1A6	—	0.978	Q9Z1A6 →
P81021	—	0.978	P81021 →
PTBP3	Polypyrimidine tract-binding protein 3	0.978	landscape →
Q9LZ82	—	0.978	Q9LZ82 →
Q5YD48	—	0.977	Q5YD48 →
Q5R9H4	—	0.977	Q5R9H4 →
Q923K9	—	0.977	Q923K9 →
O74919	—	0.977	O74919 →
P91277	—	0.977	P91277 →
C5DIR2	—	0.976	C5DIR2 →
A5DM21	—	0.976	A5DM21 →
P90727	—	0.976	P90727 →
Q756R8	—	0.976	Q756R8 →
Q9Z118	—	0.975	Q9Z118 →
HDLBP	Vigilin	0.975	landscape →
P90978	—	0.975	P90978 →
Q6CSV3	—	0.974	Q6CSV3 →