NDUFA13

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 · Q9P0J0 · NDUFA13 on Sugi Atlas →

757 patent compounds predicted against NDUFA13, 421 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL15258558 SCHEMBL15258558 0.76 8/20
R-(+)-Marmin R-(+)-Marmin (SCHEMBL27804600) 0.83 7/20
R-(+)-Marmin R-(+)-Marmin (SCHEMBL29353819) 0.83 7/20
R-(+)-Marmin R-(+)-Marmin (SCHEMBL29625637) 0.83 7/20
SCHEMBL12362713 SCHEMBL12362713 0.77 7/20
SCHEMBL15080621 SCHEMBL15080621 0.77 7/20
SCHEMBL12362702 SCHEMBL12362702 0.73 7/20
SCHEMBL31179835 SCHEMBL31179835 0.59 7/20
SCHEMBL31397586 SCHEMBL31397586 0.53 7/20
SCHEMBL31000416 SCHEMBL31000416 0.78 6/20
SCHEMBL12362734 SCHEMBL12362734 0.60 6/20
SCHEMBL13973668 SCHEMBL13973668 0.47 6/20
SCHEMBL16316892 SCHEMBL16316892 0.47 6/20
Auraptene Auraptene (SCHEMBL2535029) 1.00 5/20
Auraptene Auraptene (SCHEMBL2535034) 1.00 5/20
Umbelliprenin Umbelliprenin (SCHEMBL18265478) 0.98 5/20
Umbelliprenin Umbelliprenin (SCHEMBL26641528) 0.98 5/20
Umbelliprenin Umbelliprenin (SCHEMBL28133292) 0.98 5/20
SCHEMBL29999425 SCHEMBL29999425 0.83 5/20
SCHEMBL24700226 SCHEMBL24700226 0.81 5/20

Clinical trials — most relevant to NDUFA13 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease PHASE3COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease PHASE3COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease PHASE2RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy PHASE2ACTIVE_NOT_RECRUITING
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) PHASE1/PHASE2NOT_YET_RECRUITING
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease PHASE2COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)? PHASE1UNKNOWN
A Pilot Study to Examine the Effects of Vitamin D Supplementation on Mitochondrial Bioenergetics in Older Adults EARLY_PHASE1COMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine nanCOMPLETED
The Natural History of Mitochondrial Diseases nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Natural History in Primary Mitochondrial Myopathies nanRECRUITING
Diagnostic Odyssey Survey 2 nanCOMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases nanRECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection nanCOMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability. nanUNKNOWN
EPI-743 for Mitochondrial Respiratory Chain Diseases nanNO_LONGER_AVAILABLE
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
The International Registry for Leigh Syndrome nanRECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders nanCOMPLETED
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity nanRECRUITING
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFA13 binder may also engage these)

ProteinNameSimilarity
Q0MQ89 1.000 Q0MQ89 →
Q0MQ90 1.000 Q0MQ90 →
Q0MQ88 1.000 Q0MQ88 →
Q8RWA7 0.996 Q8RWA7 →
Q9ERS2 0.996 Q9ERS2 →
Q95KV7 0.994 Q95KV7 →
O49313 0.994 O49313 →
Q4R6H1 0.991 Q4R6H1 →
P47081 0.984 P47081 →
Q6FW43 0.982 Q6FW43 →
COX6C Cytochrome c oxidase subunit 6C 0.982 landscape →
Q2PIY2 0.981 Q2PIY2 →
Q7YRJ9 0.981 Q7YRJ9 →
Q6BY05 0.981 Q6BY05 →
Q75FA7 0.981 Q75FA7 →
P0CB94 0.981 P0CB94 →
Q7YRK3 0.981 Q7YRK3 →
Q02380 0.980 Q02380 →
Q0MQE1 0.980 Q0MQE1 →
Q3UIU2 0.980 Q3UIU2 →
Q02854 0.980 Q02854 →
NDUFB6 NADH-ubiquinone oxidoreductase B17 subunit 0.980 landscape →
Q5AXJ9 0.980 Q5AXJ9 →
Q7YRK2 0.979 Q7YRK2 →
P42117 0.979 P42117 →
Q5R7J0 0.978 Q5R7J0 →
P11950 0.978 P11950 →
P80977 0.978 P80977 →
Q6CCF6 0.978 Q6CCF6 →
Q6CK73 0.978 Q6CK73 →