NDUFB6 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20

Clinical trials — most relevant to NDUFB6 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)	PHASE1/PHASE2	NOT_YET_RECRUITING
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Prospective Observational Study of Trimetazidine Influence on Mitochondrial Metabolism in Human Heart Ventricle	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
A RETROspective Study of Patients With TK2d	nan	COMPLETED
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome	nan	COMPLETED
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity	nan	RECRUITING
Genetic Diagnosis in Inborn Errors of Metabolism	nan	ENROLLING_BY_INVITATION
Effect of Diaphragm Stimulation During Surgery	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFB6 binder may also engage these)

Protein	Name	Similarity
Q0MQE1	—	1.000	Q0MQE1 →
P0CB94	—	1.000	P0CB94 →
P0CB93	—	1.000	P0CB93 →
Q0MQE0	—	1.000	Q0MQE0 →
Q3UIU2	—	0.998	Q3UIU2 →
Q02367	—	0.995	Q02367 →
Q29259	—	0.994	Q29259 →
P11950	—	0.984	P11950 →
P0CB85	—	0.984	P0CB85 →
Q6BY05	—	0.983	Q6BY05 →
Q5AXJ9	—	0.981	Q5AXJ9 →
Q9CQ54	—	0.981	Q9CQ54 →
Q9FNE0	—	0.980	Q9FNE0 →
Q0MQ90	—	0.980	Q0MQ90 →
P0CB71	—	0.980	P0CB71 →
Q5BKW8	—	0.980	Q5BKW8 →
A8KB87	—	0.980	A8KB87 →
C4YBX9	—	0.979	C4YBX9 →
NDUFB8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	0.979	landscape →
Q0MQE7	—	0.979	Q0MQE7 →
Q8HXG5	—	0.979	Q8HXG5 →
Q7YRK2	—	0.979	Q7YRK2 →
Q42841	—	0.979	Q42841 →
Q7S7U5	—	0.979	Q7S7U5 →
Q7YRK1	—	0.978	Q7YRK1 →
Q8RWA7	—	0.978	Q8RWA7 →
Q0MQC7	—	0.978	Q0MQC7 →
O13931	—	0.978	O13931 →
C0HK65	—	0.978	C0HK65 →
Q9WU08	—	0.978	Q9WU08 →