Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.68 |
| ▸ | NDUFS8 | O00217 | 7/20 | 0.61 |
| ▸ | COXFA4 | O00483 | 7/20 | 0.61 |
| ▸ | NDUFAB1 | O14561 | 7/20 | 0.61 |
| ▸ | NDUFA1 | O15239 | 7/20 | 0.61 |
| ▸ | NDUFS4 | O43181 | 7/20 | 0.61 |
| ▸ | NDUFB5 | O43674 | 7/20 | 0.61 |
| ▸ | NDUFB3 | O43676 | 7/20 | 0.61 |
| ▸ | NDUFC1 | O43677 | 7/20 | 0.61 |
| ▸ | NDUFA2 | O43678 | 7/20 | 0.61 |
| ▸ | NDUFS5 | O43920 | 7/20 | 0.61 |
| ▸ | NDUFS7 | O75251 | 7/20 | 0.61 |
| ▸ | NDUFS2 | O75306 | 7/20 | 0.61 |
| ▸ | NDUFS6 | O75380 | 7/20 | 0.61 |
| ▸ | NDUFB1 | O75438 | 7/20 | 0.61 |
| ▸ | NDUFS3 | O75489 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351066 | 0.81 | CA12 (1.00) | CA12CA1CA7CA9CA13 | |
| Auraptene SCHEMBL2535034 | 0.76 | ALOX15 (1.00) | CA12CA1CA7CA9CA13 | |
| SCHEMBL29999425 | 0.76 | NDUFS8 (0.83) | CA12CA1CA7CA9CA13 | |
| Auraptene SCHEMBL2535029 | 0.76 | ALOX15 (1.00) | CA12CA1CA7CA9CA13 | |
| SCHEMBL18265492 | 0.76 | KDM4E (0.78) | CA12CA1CA7CA9CA13 | |
| SCHEMBL24700226 | 0.75 | NDUFS8 (0.81) | CA12CA1CA7CA9CA13 | |
| Umbelliprenin SCHEMBL28133292 | 0.75 | ALOX15 (1.00) | CA12CA1CA7CA9CA13 | |
| Umbelliprenin SCHEMBL18265478 | 0.75 | ALOX15 (1.00) | CA12CA1CA7CA9CA13 | |
| Umbelliprenin SCHEMBL26641528 | 0.75 | ALOX15 (1.00) | CA12CA1CA7CA9CA13 | |
| R-(+)-Marmin SCHEMBL29353819 | 0.75 | NDUFS8 (0.83) | CA12CA1CA7CA9CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044094-B2 | Agents for preventing and treating disorders connected to impaired neurotransmission | DSM IP ASSETS B.V. (NL) | 2011-10-25 | — | — | US | disclosed |
| US-8044094-B2 | Agents for preventing and treating disorders connected to impaired neurotransmission | DSM IP ASSETS B.V. (NL) | 2011-10-25 | — | — | US | disclosed |
| EP-1802298-B1 | NOVEL AGENTS FOR PREVENTING AND TREATING DISORDERS CONNECTED TO IMPAIRED NEUROTRANSMISSION | DSM IP ASSETS BV (NL) | 2008-12-31 | — | — | EP | disclosed |