Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 4/20 | 1.00 |
| ▸ | PABPC1 | P11940 | 3/20 | 1.00 |
| ▸ | HEXA | P06865 | 1/20 | 0.67 |
| ▸ | HEXB | P07686 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mitonafide SCHEMBL29352711 | 1.00 | FTO (1.00) | FTOPABPC1HEXAHEXBPOLB | |
| Mitonafide SCHEMBL29499462 | 1.00 | FTO (1.00) | FTOPABPC1HEXAHEXBPOLB | |
| Mitonafide SCHEMBL5166813 | 0.99 | FTO (0.98) | FTOPABPC1HEXAHEXBPOLB | |
| Mitonafide SCHEMBL5781995 | 0.94 | FTO (0.88) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL11441990 | 0.93 | PABPC1 (0.87) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL9504075 | 0.93 | FTO (0.87) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL2989147 | 0.92 | FTO (0.85) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL7712243 | 0.90 | FTO (0.81) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL9501524 | 0.89 | FTO (0.80) | FTOPABPC1HEXAHEXBPOLB | |
| SCHEMBL11550721 | 0.88 | FTO (0.79) | FTOPABPC1HEXAHEXBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8790 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| US-12522572-B2 | Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-01-13 | — | — | US | claimed |
| US-20240343697-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2024-10-17 | — | — | US | claimed |
| US-20230241057-A1 | COMPOUNDS FOR THE PREVENTION, TREATMENT AND DIAGNOSIS OF THROMBI | UNIVERSITE PARIS 13 PARIS-NORD (FR) | 2023-08-03 | — | — | US | claimed |
| EP-4157282-A1 | COMPOUNDS FOR THE PREVENTION, TREATMENT AND DIAGNOSIS OF THROMBI | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-04-05 | — | — | EP | claimed |
| US-11345956-B2 | Methods and compositions related to prostate cancer therapeutics | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-05-31 | — | — | US | claimed |
| US-11207289-B2 | Use of benzofuran lignans to induce IL-25 expression and suppress mammary tumor metastasis | ACADEMIA SINICA (TW) | 2021-12-28 | — | — | US | claimed |
| WO-2021239905-A1 | COMPOUNDS FOR THE PREVENTION, TREATMENT AND DIAGNOSIS OF THROMBI | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-12-02 | — | — | WO | claimed |
| US-10953073-B2 | XTEN conjugate compositions and methods of making same | AMUNIX PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | claimed |
| US-20210060040-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | claimed |
| WO-2002053138-A2 | TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS | SHANAHAN-PRENDERGAST ELISABETH (IE) | 2002-07-11 | — | — | WO | claimed |
| EP-1085891-A1 | MULTIBINDING INHIBITORS OF TOPOISOMERASE | Advanced Medicine, Inc. (US) | 2001-03-28 | — | — | EP | claimed |
| WO-1999064054-A9 | MULTIBINDING INHIBITORS OF TOPOISOMERASE | ADVANCED MEDICINE INC (US) | 2000-03-02 | — | — | WO | claimed |
| WO-1999064054-A1 | MULTIBINDING INHIBITORS OF TOPOISOMERASE | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |
| EP-0393575-B1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | SEARLE & CO (US) | 1994-03-16 | — | — | EP | claimed |
| EP-0502936-B1 | MITONAPHIDE INFUSION SOLUTION | KNOLL AG (DE) | 1993-07-28 | — | — | EP | claimed |
| EP-0502936-A1 | MITONAPHIDE INFUSION SOLUTION. | KNOLL AG (DE) | 1992-09-16 | — | — | EP | claimed |
| US-5057304-A | Anticarcinogenic agents | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | claimed |
| WO-1991007965-A1 | MITONAPHIDE INFUSION SOLUTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1991-06-13 | — | — | WO | claimed |
| EP-0393575-A1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | G.D. Searle & Co. (US) | 1990-10-24 | — | — | EP | claimed |