TXNDC5 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL21064822	1.00	1/20
SCHEMBL21100872	1.00	1/20
SCHEMBL21100897	1.00	1/20
SCHEMBL21100899	1.00	1/20
SCHEMBL21100898	0.89	1/20
SCHEMBL21100901	0.89	1/20
SCHEMBL25997758	0.85	1/20
SCHEMBL21101061	0.74	1/20
SCHEMBL21064814	0.74	1/20
SCHEMBL21064818	0.74	1/20
SCHEMBL21100878	0.74	1/20
SCHEMBL21064816	0.69	1/20
SCHEMBL21064820	0.69	1/20
SCHEMBL21101058	0.69	1/20
SCHEMBL25997795	0.69	1/20
SCHEMBL28392066	0.69	1/20
SCHEMBL21100774	0.69	1/20
SCHEMBL21100772	0.68	1/20
SCHEMBL21100771	0.67	1/20
SCHEMBL21101062	0.64	1/20

Clinical trials — most relevant to TXNDC5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From Real World	PHASE4	UNKNOWN
Pharmacogenomic Evaluation of Antihypertensive Responses	PHASE4	COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer	PHASE1	COMPLETED
S9304A Study of Protein Expression in Tumor Tissue Samples From Patients With Stage II or Stage III Rectal Cancer Enrolled in Clinical Trial SWOG-9304	nan	COMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Pathogenetic Basis of Aortopathy and Aortic Valve Disease	nan	ACTIVE_NOT_RECRUITING
Molecular & Clinical Evaluation of Low HDL Syndromes	nan	COMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm	nan	COMPLETED
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Genetic Association of Diabetic Retinopathy-1	nan	UNKNOWN
Autophagy Bladder Cancer	nan	UNKNOWN
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives	nan	UNKNOWN
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Identification of Diabetic Nephropathy Biomarkers Through Transcriptomics	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a TXNDC5 binder may also engage these)

Protein	Name	Similarity
Q91W90	—	0.996	Q91W90 →
Q921X9	—	0.985	Q921X9 →
PDIA5	Protein disulfide-isomerase A5	0.984	landscape →
Q9VYV3	—	0.983	Q9VYV3 →
P09102	—	0.981	P09102 →
P05307	—	0.981	P05307 →
Q2KIL5	—	0.979	Q2KIL5 →
Q5I0H9	—	0.977	Q5I0H9 →
P38657	—	0.977	P38657 →
Q53LQ0	—	0.977	Q53LQ0 →
P08003	—	0.976	P08003 →
ERP29	Endoplasmic reticulum resident protein 29	0.976	landscape →
Q4VIT4	—	0.975	Q4VIT4 →
P81628	—	0.975	P81628 →
Q10N04	—	0.975	Q10N04 →
PDIA6	Protein disulfide-isomerase A6	0.974	landscape →
P38659	—	0.974	P38659 →
P80284	—	0.974	P80284 →
P38660	—	0.974	P38660 →
Q8R4U2	—	0.974	Q8R4U2 →
P27773	—	0.973	P27773 →
Q2HWU2	—	0.973	Q2HWU2 →
P4HB	Protein disulfide-isomerase	0.973	landscape →
PDIA3	Protein disulfide-isomerase A3	0.972	landscape →
Q5RDG4	—	0.972	Q5RDG4 →
PDIA4	Protein disulfide-isomerase A4	0.971	landscape →
P52588	—	0.971	P52588 →
Q5R5B6	—	0.971	Q5R5B6 →
P57759	—	0.970	P57759 →
P81623	—	0.970	P81623 →