Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.67 |
| ▸ | MIF | P14174 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734682 | 1.00 | PLA2G7 (0.67) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL10406729 | 0.82 | PLA2G7 (0.65) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL2890648 | 0.82 | PLA2G7 (0.65) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL2532511 | 0.82 | PLA2G7 (0.65) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL3222751 | 0.80 | PLA2G7 (1.00) | PLA2G7MIFF2LMNANPC1 | |
| SCHEMBL28069049 | 0.80 | PLA2G7 (0.65) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL3222745 | 0.80 | PLA2G7 (1.00) | PLA2G7MIFF2LMNANPC1 | |
| SCHEMBL9070381 | 0.79 | PLA2G7 (0.61) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL6936380 | 0.78 | PLA2G7 (0.56) | PLA2G7MIFF2LMNATSHR | |
| SCHEMBL6936376 | 0.78 | PLA2G7 (0.56) | PLA2G7MIFF2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586307-B1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and capric acid | ROHM & HAAS (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-2586308-B1 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) and propionic acid | ROHM & HAAS (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2586309-B1 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) and maleic acid | ROHM & HAAS (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2586306-B1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and gluconic acid | ROHM & HAAS (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2586308-A1 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) and propionic acid | Rohm and Haas Company (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586310-A1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and decylene glycol | Rohm and Haas Company (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586309-A1 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) and maleic acid | Rohm and Haas Company (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586307-A1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and capric acid | Rohm and Haas Company (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586306-A1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and gluconic acid | Rohm and Haas Company (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2289335-B1 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) | ROHM & HAAS (US) | 2013-04-17 | — | — | EP | disclosed |
| US-8138212-B2 | Synergistic microbicidal compositions | ROHM AND HAAS COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| EP-2289335-A2 | Synergistic microbicidal compositions containing 2-methyl-4-isothiazolin-3-one (MIT) or 1,2-benzisothiazolin-3-one (BIT) | Rohm and Haas Company (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20110028525-A1 | Synergistic Microbicidal Compositions | DDP SPECIALTY ELECTRONIC MATERIALS US 8, LLC | 2011-02-03 | — | — | US | disclosed |