SCHEMBL110923

SCHEMBL110923

Nc1ccc(/N=N/c2ccc(S(=O)(=O)O)cc2)cc1S(=O)(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 7/20 0.60
SUMO2 P61956 5/20 0.60
SUMO1 P63165 5/20 0.60
SENP7 Q9BQF6 5/20 0.60
POLB P06746 1/20 0.56
CYP2D6 P10635 1/20 0.56
SENP3 Q9H4L4 6/20 0.54
SENP1 Q9P0U3 6/20 0.54
PHLPP2 Q6ZVD8 3/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
PTGS1 P23219 2/20 0.46
PTGS2 P35354 2/20 0.46
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
NT5E P21589 1/20 0.46
ATIC P31939 1/20 0.45
RPS6KA3 P51812 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110924 1.00 SENP2 (0.60) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL31099405 1.00 SENP2 (0.60) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL1436156 1.00 SENP2 (0.60) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL1436155 0.98 SENP2 (0.59) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL8969844 0.98 SENP2 (0.59) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL22974903 0.89 SENP2 (0.53) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL29837421 0.89 SENP2 (0.50) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL2622737 0.87 SENP2 (0.56) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL13578938 0.87 SENP2 (0.56) SENP2SUMO2SUMO1SENP7POLB
SCHEMBL9094890 0.86 SENP2 (0.63) SENP2SUMO2SUMO1SENP7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210115489-A1 NOVEL MEDIATOR KIKKOMAN CORPORATION (JP) 2021-04-22 US disclosed
EP-2577392-B1 COLOURED POLYMER PARTICLES MERCK PATENT GMBH (DE) 2019-06-26 EP disclosed
EP-3296362-A1 AZO DYES Kemira Oyj (FI) 2018-03-21 EP disclosed
EP-3296363-A1 AZO DYES Kemira Oyj (FI) 2018-03-21 EP disclosed
EP-2457955-B1 Trisazo dyes for paper dyeing KEMIRA OYJ (FI) 2017-08-09 EP disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-4460505-A Dyestuffs, processes for their preparation and their use for dyeing materials containing hydroxyl groups or nitrogen BAYER AKTIENGESELLSCHAFT (DE) 1984-07-17 US disclosed
US-4402701-A Leather dyeing agents and their preparation: membrame separation of dye mother liquor BAYER AKTIENGESELLSCHAFT (DE) 1983-09-06 US disclosed
US-4359418-A YELLOW, ORANGE COLOR CIBA-GEIGY CORPORATION (US) 1982-11-16 US disclosed
US-4337195-A FOR DYEING COTTON AND HAVING GOOD COLORFASTNESS BAYER AKTIENGESELLSCHAFT (DE) 1982-06-29 US disclosed
US-4194883-A Water-soluble disazo dyestuffs and process for coloring synthetic polyamide fibres with them HOECHST AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4145341-A WATER-SOLUBLE AZO DYES CONTAINING DIAMINOPYRIMIDINE COUPLER COMPONENTS BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4101542-A USING HYDRAZINE OR SALTS OF DITHIONOUS ACID OR HYDROXYMETHANE SULFINIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-3979378-A Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed
US-3958930-A MONOAZO, DIS3958930 MOD 3958930 AZO OR ANTHRAQUINONE DYES E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-05-25 US disclosed
US-3932376-A DYEING POLYAMIDES CROMPTON & KNOWLES CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115489-A1 NOVEL MEDIATOR MPO, EPX, LPO SENP2 2085/4885SUMO2 771/4885SUMO1 734/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 SENP2 3189/4885SUMO2 4626/4885SUMO1 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.