Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 1.00 |
| ▸ | NMT1 | P30419 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SENP5 | Q96HI0 | 6/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346925 | 0.89 | PTGS2 (0.80) | PTGS2NMT1L3MBTL1SENP5SENP2 | |
| SCHEMBL347207 | 0.87 | PTGS2 (1.00) | PTGS2L3MBTL1HPGDSMN1; SMN2HDAC8 | |
| SCHEMBL347919 | 0.87 | PTGS2 (0.76) | PTGS2NMT1SENP5SENP2SENP1 | |
| SCHEMBL10052333 | 0.86 | PTGS2 (0.74) | PTGS2NMT1SENP5SENP2SENP1 | |
| SCHEMBL10021087 | 0.84 | PTGS2 (0.72) | PTGS2NMT1SENP5SENP2SENP1 | |
| SCHEMBL347428 | 0.82 | PTGS2 (0.70) | PTGS2HPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL1623348 | 0.80 | PTGS2 (0.67) | PTGS2NMT1L3MBTL1SENP5SENP2 | |
| SCHEMBL346530 | 0.77 | MCL1 (0.62) | PTGS2HPGDHDAC8HDAC6ALDH1A1 | |
| SCHEMBL16599338 | 0.76 | PTGS2 (0.59) | PTGS2HPGDHDAC8HDAC6ALDH1A1 | |
| SCHEMBL10624354 | 0.75 | PTGS2 (0.59) | PTGS2NMT1L3MBTL1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | claimed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | claimed |
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | disclosed |
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | PTGER2, PTGES2, PTGIR | PTGS2 4/4885NMT1 752/4885L3MBTL1 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.