TCERG1

Transcription elongation regulator 1 · O14776 · TCERG1 on Sugi Atlas →

2,284 patent compounds predicted against TCERG1, 2,024 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4699731 SCHEMBL4699731 1.00 2/20
SCHEMBL4697866 SCHEMBL4697866 0.89 2/20
SCHEMBL4697696 SCHEMBL4697696 0.86 2/20
SCHEMBL4699947 SCHEMBL4699947 0.83 2/20
SCHEMBL4699140 SCHEMBL4699140 0.80 2/20
SCHEMBL4922941 SCHEMBL4922941 0.80 2/20
SCHEMBL4916509 SCHEMBL4916509 0.78 2/20
SCHEMBL4700123 SCHEMBL4700123 0.77 2/20
SCHEMBL4698636 SCHEMBL4698636 0.76 2/20
SCHEMBL4914334 SCHEMBL4914334 0.76 2/20
SCHEMBL4917606 SCHEMBL4917606 0.76 2/20
SCHEMBL4908396 SCHEMBL4908396 0.74 2/20
SCHEMBL4699183 SCHEMBL4699183 0.74 2/20
SCHEMBL4914310 SCHEMBL4914310 0.73 2/20
SCHEMBL4915098 SCHEMBL4915098 0.73 2/20
SCHEMBL4696222 SCHEMBL4696222 0.72 2/20
SCHEMBL4701699 SCHEMBL4701699 0.70 2/20
SCHEMBL4698169 SCHEMBL4698169 0.70 2/20
SCHEMBL4696537 SCHEMBL4696537 0.68 2/20
SCHEMBL4920392 SCHEMBL4920392 0.66 2/20

Clinical trials — most relevant to TCERG1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Epirubicin, Docetaxel, and Capecitabine in Treating Women With Stage IIIA or Stage IIIB Breast Cancer PHASE2COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism nanUNKNOWN
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
Identification of Viable Human Embryos Using Three Different Methods nanCOMPLETED
miRNA as a Growth Plate Marker After GH nanUNKNOWN
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions nanRECRUITING
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Human Epilepsy Genetics--Neuronal Migration Disorders Study nanRECRUITING
Finding Genes With NGS Techniques in Whom Mutations Cause Neurological Diseases nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TCERG1 binder may also engage these)

ProteinNameSimilarity
Q8CGF7 1.000 Q8CGF7 →
Q63627 0.988 Q63627 →
Q960X8 0.987 Q960X8 →
P34600 0.986 P34600 →
SMARCC2 SWI/SNF complex subunit SMARCC2 0.986 landscape →
O95104 0.986 O95104 →
Q9VIV2 0.986 Q9VIV2 →
Q9ESU6 0.985 Q9ESU6 →
B2RY56 0.984 B2RY56 →
P97496 0.984 P97496 →
Q9LV14 0.984 Q9LV14 →
Q9N3S4 0.983 Q9N3S4 →
SMARCC1 SWI/SNF complex subunit SMARCC1 0.983 landscape →
Q2T9I5 0.983 Q2T9I5 →
Q641G3 0.983 Q641G3 →
U2SURP U2 snRNP-associated SURP motif-containing protein 0.983 landscape →
BRD4 Bromodomain-containing protein 4 0.983 landscape →
Q8TC92 0.983 Q8TC92 →
Q32NW2 0.983 Q32NW2 →
Q6GLQ4 0.983 Q6GLQ4 →
P41846 0.983 P41846 →
Q99LI8 0.983 Q99LI8 →
Q0V8S0 0.982 Q0V8S0 →
Q8CH02 0.982 Q8CH02 →
Q6PGA0 0.982 Q6PGA0 →
B3MJ69 0.982 B3MJ69 →
Q8K0V4 0.982 Q8K0V4 →
Q6PDG5 0.982 Q6PDG5 →
Q9UPN6 0.982 Q9UPN6 →
Q7TSH6 0.982 Q7TSH6 →