Sugi Predict

Sugi Predict / Targets / TMEM43

TMEM43

Transmembrane protein 43 · Q9BTV4 · TMEM43 on Sugi Atlas →

0 patent compounds predicted against TMEM43, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TMEM43 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD PHASE3COMPLETED
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy PHASE2RECRUITING
StereoTactic Arrhythmia Radiotherapy in the NetherLands no. 2 PHASE2RECRUITING
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases PHASE1/PHASE2RECRUITING
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Clinical, Cellular, and Molecular Investigation Into Oculocutaneous Albinism nanCOMPLETED
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients nanCOMPLETED
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Organoid Study R334W nanWITHDRAWN
Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants nanRECRUITING
Factors Affecting Salt Intake in Young Adults nanUNKNOWN
Renal Transporters After Renal Transplantation nanUNKNOWN
Bone Microarchitecture at the Radius: a Pilot Comparison Between Children With Cystic Fibrosis and Healthy Controls nanCOMPLETED
Role of TMEM219 Marker in Type 1 Diabetes nanUNKNOWN
Hereditary Tubulointerstitial Nephritis nanCOMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
A P2X7R Single Nucleotide Mutation Promotes Chronic Allograft Vasculopathy nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Brain P-gp and Inflammation in People With Epilepsy nanCOMPLETED
Gene Expression in Inflammatory Bowel Disease nanENROLLING_BY_INVITATION
Energy Balance and Weight Gain With Ivacaftor Treatment nanCOMPLETED
Identifying Diuretic Resistance in Patients With Acute Heart Failure nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
The Natural History of TRPV4 Neuropathy nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TMEM43 binder may also engage these)

ProteinNameSimilarity
Q5R9S8 — 1.000 Q5R9S8 →
Q5XIP9 — 1.000 Q5XIP9 →
Q9DBS1 — 1.000 Q9DBS1 →
Q94HV7 — 0.976 Q94HV7 →
Q5M7X9 — 0.973 Q5M7X9 →
Q8L7N4 — 0.973 Q8L7N4 →
Q5ZJM3 — 0.972 Q5ZJM3 →
Q9CQF9 — 0.971 Q9CQF9 →
Q6NTR1 — 0.971 Q6NTR1 →
Q66GI4 — 0.970 Q66GI4 →
Q5R5N9 — 0.970 Q5R5N9 →
Q8K304 — 0.970 Q8K304 →
Q5XI31 — 0.970 Q5XI31 →
Q5ZI25 — 0.970 Q5ZI25 →
EMC1 ER membrane protein complex subunit 1 0.969 landscape →
Q5R748 — 0.969 Q5R748 →
A1L3G9 — 0.969 A1L3G9 →
Q61542 — 0.969 Q61542 →
PIGS GPI-anchor transamidase component PIGS 0.969 landscape →
Q5R8R3 — 0.969 Q5R8R3 →
Q6PD26 — 0.969 Q6PD26 →
Q7Z3D6 — 0.969 Q7Z3D6 →
DAGLB Diacylglycerol lipase-beta 0.969 landscape →
Q6NRB9 — 0.968 Q6NRB9 →
Q6AY62 — 0.968 Q6AY62 →
Q803R5 — 0.968 Q803R5 →
Q9UHG3 — 0.968 Q9UHG3 →
Q0DJC5 — 0.968 Q0DJC5 →
Q3U213 — 0.968 Q3U213 →
Q8BH86 — 0.968 Q8BH86 →