Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBAL3 | A6NHL2 | 2/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 2/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 2/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 1.00 |
| ▸ | TUBA8 | Q9NY65 | 2/20 | 1.00 |
| ▸ | PDCD4 | Q53EL6 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pironetin SCHEMBL8940436 | 1.00 | TUBAL3 (1.00) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| Pironetin SCHEMBL9305413 | 1.00 | TUBAL3 (1.00) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12632514 | 0.87 | TUBAL3 (0.77) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL370356 | 0.55 | PDCD4 (0.49) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12631630 | 0.53 | TUBAL3 (0.33) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL5767893 | 0.51 | TUBAL3 (0.33) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12209648 | 0.51 | LMNA (0.35) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL6331223 | 0.51 | — | — | |
| SCHEMBL15684941 | 0.51 | GRIK1 (0.32) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12190341 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314911-A | Antitumor, fungicide | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | claimed |
| EP-0560389-A1 | Lactone with immunosuppressive activity | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-09-15 | — | — | EP | claimed |
| JP-8048679-A | — | — | None | — | — | JP | disclosed |
| JP-5310726-A | — | — | None | — | — | JP | disclosed |
| CN-115335370-A | Fibroblast activation protein ligands for targeted delivery applications | 菲洛谢姆股份公司 | 2022-11-11 | — | — | CN | disclosed |
| EP-2583678-A2 | Small molecule immunopotentiators and assays for their detection | Novartis Vaccines and Diagnostics, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| US-20110104186-A1 | Small molecule immunopotentiators and assays for their detection | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2011-05-05 | — | — | US | disclosed |
| US-20110104186-A1 | Small molecule immunopotentiators and assays for their detection | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2011-05-05 | — | — | US | disclosed |
| JP-H0848679-A | 2-PYRANONE DERIVATIVE AND IMMUNOSUPPRESSANT CONTAINING THE SAME | SHIONOGI & CO LTD | 1996-02-20 | — | — | JP | disclosed |
| US-5314911-A | Antitumor, fungicide | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | disclosed |
| JP-H05310726-A | IMMUNOSUPPRESSIVE SUBSTANCE | SHIONOGI & CO LTD | 1993-11-22 | — | — | JP | disclosed |
| EP-0560389-A1 | Lactone with immunosuppressive activity | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110104186-A1 | Small molecule immunopotentiators and assays for their detection | ICOS, CD14, MAVS | TUBAL3 3986/4885TUBA3C 3935/4885TUBA1B 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.