Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBAL3 | A6NHL2 | 2/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 2/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 2/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 1.00 |
| ▸ | TUBA8 | Q9NY65 | 2/20 | 1.00 |
| ▸ | PDCD4 | Q53EL6 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pironetin SCHEMBL8940436 | 1.00 | TUBAL3 (1.00) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| Pironetin SCHEMBL8940434 | 1.00 | TUBAL3 (1.00) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12632514 | 0.87 | TUBAL3 (0.77) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL370356 | 0.55 | PDCD4 (0.49) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12631630 | 0.53 | TUBAL3 (0.33) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL5767893 | 0.51 | TUBAL3 (0.33) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12209648 | 0.51 | LMNA (0.35) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL6331223 | 0.51 | — | — | |
| SCHEMBL15684941 | 0.51 | GRIK1 (0.32) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL12190341 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314911-A | Antitumor, fungicide | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | claimed |
| EP-0560389-A1 | Lactone with immunosuppressive activity | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-09-15 | — | — | EP | claimed |
| JP-5310726-A | — | — | None | — | — | JP | disclosed |
| US-5314911-A | Antitumor, fungicide | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | disclosed |
| JP-H05310726-A | IMMUNOSUPPRESSIVE SUBSTANCE | SHIONOGI & CO LTD | 1993-11-22 | — | — | JP | disclosed |
| EP-0560389-A1 | Lactone with immunosuppressive activity | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |