Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060580 | 0.87 | MEN1 (0.38) | GLAALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL304993 | 0.85 | ALDH1A1 (0.51) | GLAALDH1A1MAPK1L3MBTL1CYP2C19 | |
| SCHEMBL305022 | 0.85 | GLA (0.52) | GLAALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL4143101 | 0.83 | ALDH1A1 (0.59) | GLAALDH1A1MAPK1L3MBTL1CYP2C19 | |
| SCHEMBL1365878 | 0.81 | HPGD (0.40) | ALDH1A1L3MBTL1KMT2ARAB9AGAA | |
| SCHEMBL2855104 | 0.80 | FABP7 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL305021 | 0.80 | ALDH1A1 (0.56) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL665165 | 0.80 | LMNA (0.45) | ALDH1A1LMNANPSR1NPC1RAB9A | |
| SCHEMBL20234917 | 0.80 | CYP2C19 (0.53) | GLAALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL304920 | 0.79 | NPC1 (0.55) | GLAALDH1A1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470958-B1 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470958-B1 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-13 | — | — | US | disclosed |
| US-8110678-B2 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110678-B2 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| WO-2007133706-A2 | ANTIBIOTIC-BOUND POLY (CAPROLACTONE) POLYMER | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | CAPG, PGLS, GNE | GLA 147/4885ALDH1A1 2039/4885MAPK1 4541/4885 |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | CAPG, PGLS, GNE | GLA 147/4885ALDH1A1 2039/4885MAPK1 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.