Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28174699 | 0.94 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| SCHEMBL2559145 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| SCHEMBL29954148 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| Ammonia Solution, Strong SCHEMBL28014494 | 0.85 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| SCHEMBL4194440 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| SCHEMBL16969212 | 0.80 | FFAR4 (0.50) | FFAR4FFAR1 | |
| SCHEMBL30659860 | 0.79 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTTDP1SLC6A12 | |
| SCHEMBL13226914 | 0.79 | TLR4 (0.36) | ALDH1A1POLBMAPTTDP1AKR1C3 | |
| SCHEMBL14841474 | 0.79 | HSD11B1 (0.35) | ALDH1A1POLBMAPTTDP1DGAT1 | |
| SCHEMBL24197646 | 0.79 | ANPEP (0.56) | ALDH1A1POLBMAPTTDP1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56092244-A | — | — | None | — | — | JP | disclosed |
| US-12441761-B2 | Conjugation reagents and methods using 1,2-cyclohexanediones | Encodia, Inc. (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250236632-A1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2025-07-24 | — | — | US | disclosed |
| WO-2025049804-A2 | AGENTS FOR THE TREATMENT OF NON-REPLICATING BACTERIA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024192064-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ PROTEOVANT THERAPEUTICS, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118043471-A | Process for the production of (1 r,4 r) -4-substituted cyclohexane-1-amines | 吉瑞工厂 | 2024-05-14 | — | — | CN | disclosed |
| CN-112778183-B | Nitrogen-containing ring derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| US-20230295222-A1 | Conjugation Reagents and Methods Using 1,2-Cyclohexanediones | Encodia, Inc. (US) | 2023-09-21 | — | — | US | disclosed |
| US-6056895-A | Fluorocyclohexane derivatives, and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0993459-A1 | COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057955-A1 | COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4921994-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4831059-A | ANTIEMETICS; DIARRHEA; CENTRAL NERVOUS SYSTEM | PFIZER INC. (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0048572-B1 | SUBSTITUTED 2-HYDROXYPHENYL CYCLOALKANES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0048572-A2 | Substituted 2-hydroxyphenyl cycloalkanes and pharmaceutical compositions thereof | PFIZER INC. (US) | 1982-03-31 | — | — | EP | disclosed |
| JP-S5692244-A | PREPARATION OF 4-OXOCYCLOHEXYLACETIC ACID | UBE IND LTD | 1981-07-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441761-B2 | Conjugation reagents and methods using 1,2-cyclohexanediones | TNNI3, CHD1, TNNT2 | ALDH1A1 1179/4885POLB 2875/4885MAPT 4699/4885 |
| US-20250236632-A1 | BETA-LACTAMASE INHIBITORS | MGAM, GAA, LCT | ALDH1A1 305/4885POLB 404/4885MAPT 4167/4885 |
| US-20230295222-A1 | Conjugation Reagents and Methods Using 1,2-Cyclohexanediones | TNNI3, CHD1, TNNT2 | ALDH1A1 1150/4885POLB 2499/4885MAPT 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.