Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117957 | 0.91 | MEN1 (0.34) | — | |
| SCHEMBL12267556 | 0.74 | TSHR (0.41) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL12650293 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL31218615 | 0.72 | HCAR2 (0.43) | ALDH1A1TSHR | |
| SCHEMBL12267520 | 0.71 | TSHR (0.36) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL12267515 | 0.70 | EPHX2 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL10754665 | 0.70 | EPHX2 (0.43) | THRBALDH1A1TSHR | |
| SCHEMBL15488072 | 0.70 | ATM (0.52) | ALDH1A1TSHR | |
| SCHEMBL15488073 | 0.70 | ATM (0.52) | ALDH1A1TSHR | |
| SCHEMBL7772715 | 0.70 | THRB (0.36) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115062-B2 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2015-08-25 | — | — | US | disclosed |
| US-9115062-B2 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2015-08-25 | — | — | US | disclosed |
| US-20120111233-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120111233-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120111233-A1 | FLUOROSURFACTANTS | Q6ZSR9, PFAS, FPR3 | THRB 4314/4885ALDH1A1 2058/4885TP53 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.