Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 13/20 | 0.56 |
| ▸ | GRM8 | O00222 | 9/20 | 0.56 |
| ▸ | GRM6 | O15303 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000475 | 0.80 | GRM8 (0.71) | GRM4GRM8GRM6GRM7 | |
| SCHEMBL6352033 | 0.74 | CYP2D6 (0.65) | GRM4GRM8GRM6CYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9336355 | 0.73 | CYP2D6 (0.63) | GRM4GRM8GRM6CYP2D6ALDH1A1 | |
| SCHEMBL12858790 | 0.71 | CYP2D6 (0.65) | GRM4GRM8GRM6CYP2D6ALDH1A1 | |
| SCHEMBL7604506 | 0.70 | FOLH1 (0.55) | GRM4GRM8GRM6CYP2D6GRM7 | |
| SCHEMBL8116323 | 0.69 | KYNU (0.56) | CYP2D6ALDH1A1TSHR | |
| SCHEMBL2856838 | 0.69 | POLB (0.53) | CYP2D6ALDH1A1TSHR | |
| SCHEMBL27792474 | 0.67 | TBXAS1 (0.46) | — | |
| SCHEMBL4085528 | 0.67 | GRM4 (1.00) | GRM4GRM8GRM6GRM7 | |
| SCHEMBL2419564 | 0.67 | POLB (0.65) | CYP2D6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | PTH1R, P4HA1, FGF23 | GRM4 3644/4885GRM8 4160/4885GRM6 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.