Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 5/20 | 0.65 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.65 |
| ▸ | GRM6 | O15303 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187517 | 0.80 | GRM8 (0.57) | GRM8GRM4GRM6TSHRPTPRC | |
| SCHEMBL2637757 | 0.79 | TSHR (0.59) | GRM8GRM4GRM6TSHRPTPRC | |
| SCHEMBL2637758 | 0.79 | TSHR (0.59) | GRM8GRM4GRM6TSHRPTPRC | |
| SCHEMBL10000471 | 0.79 | GRM4 (1.00) | GRM8GRM4GRM6 | |
| SCHEMBL6998770 | 0.76 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| SCHEMBL2952612 | 0.76 | POLB (0.70) | TSHRPOLBLMNA | |
| Hydrochloric Acid SCHEMBL9336447 | 0.75 | POLB (0.73) | TSHRPOLBLMNA | |
| SCHEMBL10000477 | 0.74 | GRM8 (0.69) | GRM8GRM4GRM6TSHRLMNA | |
| SCHEMBL2036257 | 0.73 | TSHR (0.59) | GRM8GRM4GRM6TSHRPOLB | |
| SCHEMBL6545015 | 0.73 | TSHR (0.62) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | PTH1R, P4HA1, FGF23 | GRM8 4160/4885GRM4 3644/4885GRM6 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.