SCHEMBL1000048

SCHEMBL1000048

NC(=O)[C@@H](O)[C@H](O)[C@@H](O)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.37
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.35
HIF1A Q16665 1/20 0.35
ACHE P22303 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445885 0.96 PGD (0.36) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL18902784 0.92 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL4449219 0.92 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL6686437 0.92 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL987602 0.92 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL7093505 0.84 LMNA (0.42) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL1874716 0.84 LMNA (0.42) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL77247 0.84 LMNA (0.42) PGDLMNAALDH1A1OR51E2TDP1
Propyne SCHEMBL6019135 0.83 PGD (0.34) PGD
SCHEMBL16126131 0.81 TP53 (0.33) PGDLMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160194446-A1 HYDROXYPOLYAMIDE GEL FORMING AGENTS UNIV MONTANA (US) 2016-07-07 US claimed
US-20140228452-A1 HYDROXYPOLYAMIDE GEL FORMING AGENTS SILICON VALLEY BANK 2014-08-14 US claimed
JP-2011503331-A 2011-01-27 JP claimed
EP-2209835-A2 HYDROXYPOLYAMIDE GEL FORMING AGENTS The University Of Montana (US) 2010-07-28 EP claimed
WO-2009065143-A2 HYDROXYPOLYAMIDE GEL FORMING AGENTS THE UNIVERSITY OF MONTANA (US) 2009-05-22 WO claimed
US-20090131259-A1 Hydroxypolyamide Gel Forming Agents SILICON VALLEY BANK 2009-05-21 US claimed
US-20170107327-A1 HYDROXYPOLYAMIDE GEL FORMING AGENTS THE UNIV OF MONTANA (US) 2017-04-20 US disclosed
US-9505882-B2 Hydroxypolyamide gel forming agents THE UNIVERSITY OF MONTANA (US) 2016-11-29 US disclosed
US-20160194446-A1 HYDROXYPOLYAMIDE GEL FORMING AGENTS UNIV MONTANA (US) 2016-07-07 US disclosed
US-9315624-B2 Hydroxypolyamide gel forming agents THE UNIVERSITY OF MONTANA (US) 2016-04-19 US disclosed
CN-103725619-B The simple and fast isolation and purification culture method of Agrocybe cylindracea YUNNAN UNIVERSITY (CN) 2015-09-30 CN disclosed
US-20140228452-A1 HYDROXYPOLYAMIDE GEL FORMING AGENTS SILICON VALLEY BANK 2014-08-14 US disclosed
CN-103725619-A Simple and rapid separation and purification culture method of antler xylaria UNIV YUNNAN 2014-04-16 CN disclosed
EP-2209835-A2 HYDROXYPOLYAMIDE GEL FORMING AGENTS The University Of Montana (US) 2010-07-28 EP disclosed
WO-2009065143-A2 HYDROXYPOLYAMIDE GEL FORMING AGENTS THE UNIVERSITY OF MONTANA (US) 2009-05-22 WO disclosed
US-20090131259-A1 Hydroxypolyamide Gel Forming Agents SILICON VALLEY BANK 2009-05-21 US disclosed
EP-1569982-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT RANDOM POLYHYDROXYPOLYAMIDES THE UNIVERSITY OF MONTANA (US) 2005-09-07 EP disclosed
US-20040158029-A1 Method for preparing high molecular weight random polyhydroxypolyamides SILICON VALLEY BANK 2004-08-12 US disclosed
WO-2004052959-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT RANDOM POLYHYDROXYPOLYAMIDES THE UNIVERSITY OF MONTANA (US) 2004-06-24 WO disclosed
US-4216076-A POLYALKYLENEOXY SULFOXY SALT NL INDUSTRIES, INC. (US) 1980-08-05 US disclosed