SCHEMBL4449219

SCHEMBL4449219

NC(=O)C(O)C(O)C(O)C(O)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.37
LMNA P02545 3/20 0.36
ALDH1A1 P00352 1/20 0.36
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.35
HIF1A Q16665 1/20 0.35
ACHE P22303 1/20 0.33
PDE4A P27815 1/20 0.33
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987602 1.00 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL6686437 1.00 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL18902784 1.00 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL4445885 0.96 PGD (0.36) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL1000048 0.92 PGD (0.37) PGDLMNAALDH1A1OR51E2TDP1
SCHEMBL5063165 0.87 TSHR (0.50) PGDLMNAALDH1A1TSHRHIF1A
SCHEMBL31134456 0.87 TSHR (0.50) PGDLMNAALDH1A1TSHRHIF1A
SCHEMBL31482274 0.87 TSHR (0.50) PGDLMNAALDH1A1TSHRHIF1A
SCHEMBL22388686 0.87 TSHR (0.50) PGDLMNAALDH1A1TSHRHIF1A
SCHEMBL31028137 0.87 TSHR (0.50) PGDLMNAALDH1A1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097180-A1 BIOBASED COMPOUNDS FOR POLYMER PRODUCTION SOLUGEN, INC. (US) 2025-05-08 WO claimed
US-20250084031-A1 METHOD OF PREPARING GLUCOSE-DERIVED ADIPONITRILE AND A METHOD OF DEHYDRATING BIOMASS-DERIVED AMIDE COMPOUND HYUNDAI MOTOR COMPANY (KR) 2025-03-13 US claimed
US-20220306610-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2022-09-29 US claimed
CN-114133844-A High-weather-resistance powder coating for metal guardrail and preparation method and application thereof 苏亿护栏有限公司 2022-03-04 CN claimed
CN-111662423-A Preparation method of hydroxyl functionalized waterborne polyurethane 中国科学院山西煤炭化学研究所 2020-09-15 CN claimed
CN-101001615-B Drug delivery product and method NEXMED HOLDINGS INC 2012-07-04 CN claimed
EP-3565808-B1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX INC (US) 2026-03-04 EP disclosed
WO-2025097180-A1 BIOBASED COMPOUNDS FOR POLYMER PRODUCTION SOLUGEN, INC. (US) 2025-05-08 WO disclosed
US-12281103-B2 Compounds useful for treating gastrointestinal tract disorders ARDELYX, INC. (US) 2025-04-22 US disclosed
US-20250084031-A1 METHOD OF PREPARING GLUCOSE-DERIVED ADIPONITRILE AND A METHOD OF DEHYDRATING BIOMASS-DERIVED AMIDE COMPOUND HYUNDAI MOTOR COMPANY (KR) 2025-03-13 US disclosed
CN-114008065-B Glycyrrhetinic acid derivatives for the treatment of hyperkalemia 阿德利克斯股份有限公司 2025-03-11 CN disclosed
US-20250067907-A1 COMPOUNDS AND METHODS FOR TREATING HYPERKALEMIA ARDELYX, INC. (US) 2025-02-27 US disclosed
US-20240317719-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2024-09-26 US disclosed
CN-114008065-A Glycyrrhetinic acid derivatives for treating hyperkalemia 阿德利克斯股份有限公司 2022-02-01 CN disclosed
CN-111662423-A Preparation method of hydroxyl functionalized waterborne polyurethane 中国科学院山西煤炭化学研究所 2020-09-15 CN disclosed
CN-111132968-A N-alkyl-D-glucaric acid-6-amide derivatives and alkylammonium salts thereof as intermediates for the preparation of D-glucaric acid-6, 3-lactone monoamide 巴斯夫欧洲公司 2020-05-08 CN disclosed
EP-3565808-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS Ardelyx, Inc. (US) 2019-11-13 EP disclosed
WO-2018129552-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2018-07-12 WO disclosed
EP-2101220-A1 Protective overcoat of photoreceptor having a charge transport compound Xerox Corporation (US) 2009-09-16 EP disclosed
US-20090214969-A1 PROTECTIVE OVERCOAT OF PHOTORECEPTOR HAVING A CHARGE TRANSPORT COMPOUND XEROX CORPORATION (US) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306610-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS SLC10A2, FABP2, SLC10A1 PGD 920/4885LMNA 4122/4885ALDH1A1 1579/4885
US-20250084031-A1 METHOD OF PREPARING GLUCOSE-DERIVED ADIPONITRILE AND A METHOD OF DEHYDRATING BIOMASS-DERIVED AMIDE COMPOUND SLC2A8, FABP4, SLC2A4 PGD 38/4885LMNA 2034/4885ALDH1A1 1725/4885
US-20250067907-A1 COMPOUNDS AND METHODS FOR TREATING HYPERKALEMIA REN, NHERF1, KCNJ11 PGD 2223/4885LMNA 1098/4885ALDH1A1 1308/4885
US-12281103-B2 Compounds useful for treating gastrointestinal tract disorders SLC10A2, FABP2, SLC10A1 PGD 920/4885LMNA 4122/4885ALDH1A1 1579/4885
US-20240317719-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS SLC10A2, FABP2, SLC10A1 PGD 920/4885LMNA 4122/4885ALDH1A1 1579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.