Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449219 | 1.00 | PGD (0.37) | PGDLMNAALDH1A1OR51E2TDP1 | |
| SCHEMBL987602 | 1.00 | PGD (0.37) | PGDLMNAALDH1A1OR51E2TDP1 | |
| SCHEMBL18902784 | 1.00 | PGD (0.37) | PGDLMNAALDH1A1OR51E2TDP1 | |
| SCHEMBL4445885 | 0.96 | PGD (0.36) | PGDLMNAALDH1A1OR51E2TDP1 | |
| SCHEMBL1000048 | 0.92 | PGD (0.37) | PGDLMNAALDH1A1OR51E2TDP1 | |
| SCHEMBL5063165 | 0.87 | TSHR (0.50) | PGDLMNAALDH1A1TSHRHIF1A | |
| SCHEMBL31134456 | 0.87 | TSHR (0.50) | PGDLMNAALDH1A1TSHRHIF1A | |
| SCHEMBL31482274 | 0.87 | TSHR (0.50) | PGDLMNAALDH1A1TSHRHIF1A | |
| SCHEMBL22388686 | 0.87 | TSHR (0.50) | PGDLMNAALDH1A1TSHRHIF1A | |
| SCHEMBL31028137 | 0.87 | TSHR (0.50) | PGDLMNAALDH1A1TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024258458-A1 | HALOGENATED OLEFIN-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION | COVESTRO LLC (US) | 2024-12-19 | — | — | WO | claimed |
| US-20040220259-A1 | Topical treatment of dermatological disorders associated with reactive or dilated blood vessels | YU RUEY J (US) | 2004-11-04 | — | — | US | claimed |
| WO-2004093722-A2 | TOPICAL TREATMENT OF DERMATOLOGICAL DISORDERS ASSOCIATED WITH REACTIVE OR DILATED BLOOD VESSELS | YU RUEY J (US) | 2004-11-04 | — | — | WO | claimed |
| EP-0994111-B1 | TETRAHYDROFURAN DERIVATIVES | TAKARA SHUZO CO (JP) | 2003-06-04 | — | — | EP | claimed |
| WO-2025034923-A1 | METHODS AND COMPOSITIONS FOR THE PROUDCTION OF AMIDES FROM SUGAR LACTONES | SOLUGEN, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2024258458-A1 | HALOGENATED OLEFIN-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION | COVESTRO LLC (US) | 2024-12-19 | — | — | WO | disclosed |
| EP-4444780-A1 | HCFO-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION | Covestro LLC (US) | 2024-10-16 | — | — | EP | disclosed |
| US-11767394-B2 | HCFO-containing polyurethane foam-forming compositions, related foams and methods for their production | COVESTRO LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230183413-A1 | HCFO-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION | COVESTRO LLC | 2023-06-15 | — | — | US | disclosed |
| WO-2023107226-A1 | HCFO-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION | COVESTRO LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| US-10829439-B2 | Method for producing adipamide as intermediate for production of raw material for bio-based nylon | HYUNDAI MOTOR COMPANY (KR) | 2020-11-10 | — | — | US | disclosed |
| US-20200071262-A1 | METHOD FOR PRODUCING ADIPAMIDE AS INTERMEDIATE FOR PRODUCTION OF RAW MATERIAL FOR BIO-BASED NYLON | HYUNDAI MOTOR COMPANY (KR) | 2020-03-05 | — | — | US | disclosed |
| US-10414710-B1 | Method for manufacturing adipic acid using biomass | HYUNDAI MOTOR COMPANY (KR) | 2019-09-17 | — | — | US | disclosed |
| US-20170275569-A1 | HAND DISHWASHING DETERGENT HAVING AN IMPROVED EFFECT AGAINST STARCH | HENKEL AG & CO. KGAA (DE) | 2017-09-28 | — | — | US | disclosed |
| US-8329631-B2 | Hand dishwashing detergent | HENKEL AG & CO. KGAA (DE) | 2012-12-11 | — | — | US | disclosed |
| US-20040220259-A1 | Topical treatment of dermatological disorders associated with reactive or dilated blood vessels | YU RUEY J (US) | 2004-11-04 | — | — | US | disclosed |
| WO-2004093722-A2 | TOPICAL TREATMENT OF DERMATOLOGICAL DISORDERS ASSOCIATED WITH REACTIVE OR DILATED BLOOD VESSELS | YU RUEY J (US) | 2004-11-04 | — | — | WO | disclosed |
| EP-0994111-B1 | TETRAHYDROFURAN DERIVATIVES | TAKARA SHUZO CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6133238-A | ANTICANCER ACTION | TAKARA SHUZO CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0994111-A1 | TETRAHYDROFURAN DERIVATIVES | TAKARA SHUZO CO. LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220259-A1 | Topical treatment of dermatological disorders associated with reactive or dilated blood vessels | AKR1C3, ALDOA, AKR1C2 | PGD 13/4885LMNA 1780/4885ALDH1A1 83/4885 |
| US-20200071262-A1 | METHOD FOR PRODUCING ADIPAMIDE AS INTERMEDIATE FOR PRODUCTION OF RAW MATERIAL FOR BIO-BASED NYLON | IDH2, HK2, SLC2A2 | PGD 36/4885LMNA 3347/4885ALDH1A1 503/4885 |
| US-10414710-B1 | Method for manufacturing adipic acid using biomass | ADIPOR2, HK2, HAO2 | PGD 34/4885LMNA 3405/4885ALDH1A1 519/4885 |
| US-10829439-B2 | Method for producing adipamide as intermediate for production of raw material for bio-based nylon | HK2, ADIPOR2, NOS2 | PGD 55/4885LMNA 3753/4885ALDH1A1 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.