Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.69 |
| ▸ | GRM8 | O00222 | 4/20 | 0.69 |
| ▸ | GRM6 | O15303 | 2/20 | 0.48 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027421 | 0.81 | GRM4 (1.00) | GRM4GRM8GRM6GRM7 | |
| SCHEMBL20614246 | 0.78 | RAB9A (0.57) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL10000480 | 0.78 | GRM8 (0.72) | GRM4GRM8GRM6GRM7MAPT | |
| SCHEMBL10000482 | 0.77 | GRM8 (0.72) | GRM4GRM8GRM6GRM7MAPT | |
| SCHEMBL7031564 | 0.75 | RAB9A (0.60) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL8297049 | 0.74 | RAB9A (0.59) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL345717 | 0.74 | RAB9A (0.59) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL10728316 | 0.74 | RAB9A (0.53) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL15649780 | 0.72 | RAB9A (0.56) | GRM4GRM8RAB9AMAPTKDM4E | |
| SCHEMBL13187158 | 0.71 | GRM4 (0.81) | GRM4GRM8GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | PTH1R, P4HA1, FGF23 | GRM4 3644/4885GRM8 4160/4885GRM6 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.