Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712767 | 0.74 | PIM1 (0.31) | — | |
| SCHEMBL20817157 | 0.73 | MEN1 (0.32) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL5536622 | 0.70 | XIAP (0.68) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL12744504 | 0.69 | ALOX15 (0.32) | MAPTMAPK1CYP3A4CDC25BLMNA | |
| SCHEMBL11790353 | 0.68 | XIAP (0.41) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL5712735 | 0.68 | KDM4E (0.31) | ALDH1A1MAPTMEN1BLMKMT2A | |
| SCHEMBL3624714 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL9875880 | 0.67 | STAT3 (0.37) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL3968141 | 0.65 | STAT3 (0.59) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL8138381 | 0.65 | MEN1 (0.34) | ALDH1A1MAPTMEN1MAPK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207229-B1 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2012-06-26 | — | — | US | disclosed |
| US-8207229-B1 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2012-06-26 | — | — | US | disclosed |
| US-8003824-B2 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-8003824-B2 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| EP-2257523-B1 | PREPARATION OF HYDROQUINONE AMIDE COMPOUNDS WITH ANTIOXIDANT PROPERTIES | CATALYS SAS (FR) | 2011-08-10 | — | — | EP | disclosed |
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | CATALYS SAS (FR) | 2011-01-27 | — | — | US | disclosed |
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | CATALYS SAS (FR) | 2011-01-27 | — | — | US | disclosed |
| WO-2009115707-A2 | PREPARATION OF HYDROQUINONE AMIDE COMPOUNDS WITH ANTIOXIDANT PROPERTIES. | CATALYS SAS (FR) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | NQO1, TYR, AHR | ALDH1A1 27/4885MAPT 4244/4885MEN1 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.