Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536908 | 0.90 | LMNA (0.54) | LMNACASP2MCL1CNR1HPGD | |
| SCHEMBL17736080 | 0.89 | CASP2 (0.53) | CASP2CNR1HPGDNAAAFAAH | |
| SCHEMBL16384356 | 0.85 | CASP2 (0.65) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL10025175 | 0.84 | CASP2 (0.52) | CASP2HPGDNAAAFAAHCTSD | |
| SCHEMBL7134927 | 0.83 | CASP2 (0.45) | CASP2MCL1CNR1HPGDNAAA | |
| SCHEMBL17736082 | 0.79 | SLC6A5 (0.42) | LMNACASP2HPGDNAAAKMT2A | |
| SCHEMBL14076479 | 0.78 | TSHR (0.41) | LMNAHPGDKMT2ACA1CA2 | |
| SCHEMBL3351989 | 0.78 | CASP2 (0.56) | CASP2MCL1CNR1NAAAFAAH | |
| SCHEMBL12523062 | 0.78 | CASP2 (0.59) | LMNACASP2CNR1HPGDNAAA | |
| SCHEMBL12417550 | 0.78 | TSHR (0.47) | LMNACASP2CNR1NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040390-A1 | Method for Introducing Protein and/or Peptide Into Cell | Nippon Shokubai Com, Ltd. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-7824910-B2 | Generating polyamine/polypeptide conjugate and transferring polypeptide into tissues; regeneration medicine; tissue engineering | NIPPON SHOKUBAI CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-7824910-B2 | Generating polyamine/polypeptide conjugate and transferring polypeptide into tissues; regeneration medicine; tissue engineering | NIPPON SHOKUBAI CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-7252960-B2 | Test kit for intracellular introduction of protein and/or peptide and method of intracellular introduction | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |