Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000782 | 0.90 | LMNA (0.43) | LMNACASP2MCL1CNR1NAAA | |
| SCHEMBL12523062 | 0.87 | CASP2 (0.59) | LMNACASP2CNR1NAAAHPGD | |
| SCHEMBL9518772 | 0.85 | CASP2 (0.68) | CASP2NAAAHPGDFAAHKMT2A | |
| SCHEMBL7134927 | 0.84 | CASP2 (0.45) | CASP2MCL1CNR1NAAAHPGD | |
| SCHEMBL9518701 | 0.84 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX1 | |
| SCHEMBL9502450 | 0.84 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX1 | |
| SCHEMBL2616294 | 0.84 | CASP2 (0.55) | LMNACASP2CNR1NAAAHPGD | |
| SCHEMBL1146790 | 0.84 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX1 | |
| SCHEMBL3351989 | 0.83 | CASP2 (0.56) | CASP2MCL1CNR1NAAAFAAH | |
| SCHEMBL12312998 | 0.83 | CASP2 (0.44) | CASP2MCL1CNR1NAAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696234-B2 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. | 2003-10-09 | — | — | US | disclosed |
| US-5008395-A | Forming hydrochloride salt, removing excess hydrogen chloride, cooling until crystals form, ripening, filtering | ROHM AND HAAS COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0375265-A2 | Purification of isothiazolones | ROHM AND HAAS COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | NRP1, NR2E3, SCN1B | LMNA 4737/4885CASP2 2309/4885MCL1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.