Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | FLT3 | P36888 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KIT | P10721 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001085 | 0.88 | MAPT (0.71) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001080 | 0.88 | MAPT (0.64) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001089 | 0.88 | FLT3 (0.69) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001084 | 0.86 | ABCB1 (0.69) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001103 | 0.84 | HSD17B2 (0.66) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001079 | 0.83 | MAPT (0.67) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL11910055 | 0.82 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL10001096 | 0.80 | FLT3 (0.72) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL1973279 | 0.79 | MEN1 (0.65) | ALDH1A1MEN1KMT2AFLT3MAPT | |
| SCHEMBL1976108 | 0.79 | MEN1 (0.65) | ALDH1A1MEN1KMT2AFLT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |
| US-20110243894-A1 | METHODS OF TREATING HEPATITIS C VIRUS INFECTION | KADMON CORPORATION, LLC | 2011-10-06 | — | — | US | disclosed |
| US-20110243894-A1 | METHODS OF TREATING HEPATITIS C VIRUS INFECTION | KADMON CORPORATION, LLC | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243894-A1 | METHODS OF TREATING HEPATITIS C VIRUS INFECTION | HAVCR2, LIPC, FABP1 | ALDH1A1 908/4885MEN1 4813/4885KMT2A 3148/4885 |
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | HTR2C, GRIN2C, HTR5A | ALDH1A1 1018/4885MEN1 4859/4885KMT2A 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.