Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | GABRP | O00591 | 4/20 | 0.72 |
| ▸ | GABRD | O14764 | 4/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.72 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.72 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.72 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.72 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.72 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.72 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.72 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.72 |
| ▸ | GABRE | P78334 | 4/20 | 0.72 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.72 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.72 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.72 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352089 | 0.89 | ABCB1 (0.77) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10001090 | 0.88 | AKT1 (0.71) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10001081 | 0.88 | KMT2A (0.63) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10001096 | 0.86 | FLT3 (0.72) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1974890 | 0.85 | KMT2A (0.63) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1975145 | 0.85 | KMT2A (0.63) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL29004586 | 0.84 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL142093 | 0.84 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL29692708 | 0.84 | KMT2A (1.00) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24088771 | 0.83 | CBS (0.82) | KMT2AGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170239211-A1 | USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF FIBROSIS USING EMT INHIBITORY ACTIVITY | OSTEONEUROGEN INC. (KR) | 2017-08-24 | — | — | US | disclosed |
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170239211-A1 | USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF FIBROSIS USING EMT INHIBITORY ACTIVITY | CDH1, SMAD3, SMAD2 | KMT2A 2795/4885GABRP 4689/4885GABRD 4747/4885 |
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | HTR2C, GRIN2C, HTR5A | KMT2A 1058/4885GABRP 76/4885GABRD 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.