SCHEMBL10001296

SCHEMBL10001296

COc1ccc(C(C)(C)c2ccc(OC(=O)CC(C)=O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
APEX1 P27695 1/20 0.49
MAPK1 P28482 1/20 0.49
RECQL P46063 1/20 0.49
MAPT P10636 2/20 0.46
KMT2A Q03164 4/20 0.46
HTT P42858 2/20 0.46
GAA P10253 4/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
EPHX2 P34913 1/20 0.43
NR1H4 Q96RI1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2703212 0.94 ALDH1A1 (0.47) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL13633980 0.89 KMT2A (0.51) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL15001277 0.85 ALDH1A1 (0.46) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL12761952 0.84 MAPT (0.47) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL17124304 0.84 LMNA (0.42) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL9999552 0.84 KMT2A (0.47) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL15001298 0.84 EGFR (0.49) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL14580011 0.83 LMNA (0.52) LMNAALDH1A1TDP1HSD17B10MAPK1
SCHEMBL6253299 0.83 MAPT (0.51) LMNAALDH1A1TDP1HSD17B10ALOX15
SCHEMBL16093179 0.83 KMT2A (0.53) LMNAALDH1A1TDP1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed
US-20150050588-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed
US-20150050587-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed
US-20150024310-A1 POLYMER FOR CHARGE GENERATION LAYER AND CHARGE TRANSPORT LAYER FORMULATION XEROX CORPORATION 2015-01-22 US disclosed
US-8835085-B2 Low strain anti-curl back coating for flexible imaging members XEROX CORPORATION (US) 2014-09-16 US disclosed
US-20140087297-A1 LOW STRAIN ANTI-CURL BACK COATING FOR FLEXIBLE IMAGING MEMBERS XEROX CORPORATION (US) 2014-03-27 US disclosed
US-8545738-B2 Stabilized photochromic ink for reusable paper annotation XEROX CORPORATION (US) 2013-10-01 US disclosed
US-20130143016-A1 ALTERNATE ANTICURL BACK COATING FORMULATION XEROX CORPORATION (US) 2013-06-06 US disclosed
US-8303858-B2 Photochromic polymer with binder XEROX CORPORATION (US) 2012-11-06 US disclosed
US-8293438-B2 Erasable media with binder XEROX CORPORATION (US) 2012-10-23 US disclosed
US-20120038718-A1 STABILIZED PHOTOCHROMIC INK FOR REUSABLE PAPER ANNOTATION XEROX CORPORATION (US) 2012-02-16 US disclosed
US-20110215283-A1 PHOTOCHROMIC POLYMER WITH BINDER XEROX CORPORATION (US) 2011-09-08 US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 US disclosed
US-20110130279-A1 ERASABLE MEDIA WITH BINDER XEROX CORPORATION (US) 2011-06-02 US disclosed