Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PRKACA | P17612 | 6/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899314 | 0.85 | AHCY (0.82) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL10001410 | 0.84 | PRKACA (0.83) | AHCYHSP90AA1ADORA3HSP90B1ADORA2A | |
| SCHEMBL7851974 | 0.82 | PARP1 (0.67) | AHCYTHRBPRKACA | |
| SCHEMBL10001413 | 0.79 | ADORA3 (1.00) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL12119006 | 0.79 | ADORA3 (1.00) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL8373480 | 0.76 | ADORA3 (0.85) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL10001407 | 0.75 | AHCY (0.80) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL29360147 | 0.75 | PRKACA (1.00) | ADORA3HSP90B1ADORA2APRKACAROCK2 | |
| SCHEMBL20579582 | 0.75 | AHCY (1.00) | AHCYTSHRKMT2AHSP90AA1ADORA3 | |
| SCHEMBL32660834 | 0.74 | PRKACA (1.00) | AHCYADORA3HSP90B1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | ADK, PRKCH, DMPK | AHCY 1747/4885TSHR 3832/4885KMT2A 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.