Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267907 | 1.00 | GAA (0.75) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL10262186 | 1.00 | GAA (0.75) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL10262424 | 1.00 | GAA (0.75) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL10261900 | 1.00 | GAA (0.75) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL10262863 | 0.98 | L3MBTL1 (0.74) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL10261674 | 0.94 | L3MBTL1 (0.73) | GAAL3MBTL1ALDH1A1HTTMAOB | |
| SCHEMBL2370175 | 0.87 | L3MBTL1 (0.69) | GAAL3MBTL1ALDH1A1HTTTP53 | |
| SCHEMBL9448865 | 0.86 | ALDH1A1 (0.88) | GAAL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL13346213 | 0.86 | ALDH1A1 (0.88) | GAAL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL8379459 | 0.86 | ALDH1A1 (0.88) | GAAL3MBTL1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093307-B2 | Silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2012-01-10 | — | — | US | disclosed |
| US-20090208374-A1 | Novel silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208374-A1 | Novel silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports | SELE, ICAM1, SDC1 | GAA 4511/4885L3MBTL1 1390/4885ALDH1A1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.