SCHEMBL10001617

SCHEMBL10001617

C=Cc1ccc(C(CC)COC=O)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TYR P14679 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11215658 0.80 ALDH1A1 (0.50) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL10526745 0.80 ESR1 (0.40) ALDH1A1HDAC8HDAC6ESR1ESR2
SCHEMBL7232754 0.80 CCR5 (0.41) ALDH1A1
SCHEMBL27632183 0.77 CYP17A1 (0.37) ALDH1A1HDAC8HDAC6
SCHEMBL10001616 0.75 CHRNB2 (0.38) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL19937453 0.75 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL5034586 0.74 TAS1R3 (0.45) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL16407305 0.74 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL19968156 0.73 ALDH1A1 (0.41) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL6285951 0.73 ESR1 (0.59) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120160095-A1 Novel Nanoporous Supported Lyotropic Liquid Crystal Polymer Membranes and Methods of Preparing and Using Same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2012-06-28 US disclosed