Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | TRHR | P34981 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000430 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TRHR | |
| SCHEMBL2182026 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TRHR | |
| Bromide SCHEMBL7325613 | 0.99 | DPP4 (0.43) | DPP4DPP8DPP9TRHR | |
| Bromide SCHEMBL5735593 | 0.99 | DPP4 (0.43) | DPP4DPP8DPP9TRHR | |
| Bromide SCHEMBL7325997 | 0.99 | DPP4 (0.43) | DPP4DPP8DPP9TRHR | |
| SCHEMBL10454953 | 0.96 | TRHR (0.43) | DPP4DPP8DPP9TRHR | |
| SCHEMBL10454951 | 0.96 | TRHR (0.43) | DPP4DPP8DPP9TRHR | |
| SCHEMBL5734357 | 0.91 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL4595209 | 0.91 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL4595206 | 0.91 | DPP4 (0.44) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382842-B1 | NOOTROPIC | Grünenthal GmbH (DE) | 1993-09-22 | — | — | EP | claimed |
| US-5118670-A | PROCESS AND COMPOSITION FOR INCREASING BRAIN DOPAMINE RELEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0382842-A1 | NOOTROPIC | Grünenthal GmbH (DE) | 1990-08-22 | — | — | EP | claimed |
| EP-0373904-A1 | Process and composition for increasing brain dopamine release | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-06-20 | — | — | EP | claimed |
| EP-0194443-B1 | NOVEL PEPTIDES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PRODUCTION | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-30 | — | — | EP | claimed |
| EP-0194443-A2 | Novel peptides, compositions containing them and processes for their production | TANABE SEIYAKU CO., LTD. (JP) | 1986-09-17 | — | — | EP | claimed |
| EP-0168042-A2 | Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-15 | — | — | EP | claimed |
| US-4045556-A | ANTIDEPRESSANTS, PYSCHOSTIMULANTS; SILYLATION | SCHWERTNER EBERHARD | 1977-08-30 | — | — | US | claimed |
| JP-63316724-A | — | — | None | — | — | JP | disclosed |
| JP-7082166-A | — | — | None | — | — | JP | disclosed |
| JP-62022797-A | — | — | None | — | — | JP | disclosed |
| JP-1025728-A | — | — | None | — | — | JP | disclosed |
| US-11191805-B2 | Cyclic prosaposin peptides and uses thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-12-07 | — | — | US | disclosed |
| WO-2011008005-A3 | METHOD FOR PREPARING HISTIDYL-PROLINAMIDE DERIVATIVES USING A POLYMER SOLID PHASE SUPPORT | 웰이앤씨 주식회사 (KR) | 2011-06-23 | — | — | WO | disclosed |
| JP-S63316724-A | ANTICONVULSANT | NIPPON SHINYAKU CO LTD | 1988-12-26 | — | — | JP | disclosed |
| US-4711878-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1987-12-08 | — | — | US | disclosed |
| US-4665056-A | CENTRAL NERVOUS SYSTEM DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| JP-S6222797-A | NOVEL PEPTIDE AND PRODUCTION THEREOF | TANABE SEIYAKU CO LTD | 1987-01-30 | — | — | JP | disclosed |
| EP-0194443-A2 | Novel peptides, compositions containing them and processes for their production | TANABE SEIYAKU CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0168042-A2 | Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |