Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454953 | 1.00 | TRHR (0.43) | TRHRDPP4DPP8DPP9ACE | |
| SCHEMBL4595206 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL4595209 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL1000430 | 0.96 | DPP4 (0.44) | TRHRDPP4DPP8DPP9 | |
| SCHEMBL2182026 | 0.96 | DPP4 (0.44) | TRHRDPP4DPP8DPP9 | |
| SCHEMBL5734357 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL1000429 | 0.96 | DPP4 (0.44) | TRHRDPP4DPP8DPP9 | |
| Bromide SCHEMBL5735593 | 0.95 | DPP4 (0.43) | TRHRDPP4DPP8DPP9 | |
| Bromide SCHEMBL7325997 | 0.95 | DPP4 (0.43) | TRHRDPP4DPP8DPP9 | |
| Bromide SCHEMBL7325613 | 0.95 | DPP4 (0.43) | TRHRDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373904-A1 | Process and composition for increasing brain dopamine release | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-06-20 | — | — | EP | claimed |