Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704320 | 0.96 | APP (0.53) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL8499580 | 0.87 | IDO1 (0.61) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL6496291 | 0.85 | L3MBTL1 (0.65) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL9671825 | 0.85 | TSHR (0.43) | TDP1L3MBTL1IDO1AGXTLTA4H | |
| SCHEMBL2624069 | 0.83 | IDO1 (0.57) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL34413 | 0.83 | IDO1 (0.67) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL17230489 | 0.82 | TDP1 (0.56) | TDP1L3MBTL1IDO1AGXTAPP | |
| SCHEMBL12462062 | 0.82 | TDP1 (0.56) | TDP1L3MBTL1IDO1AGXTAPP | |
| Potassium SCHEMBL1477050 | 0.81 | IDO1 (0.64) | TDP1L3MBTL1IDO1AGXTAPP | |
| Hydrochloric Acid SCHEMBL28912134 | 0.81 | IDO1 (0.68) | TDP1L3MBTL1IDO1AGXTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007396-B1 | Enfumafungin derivatives as antifungal agents | MERCK SHARP & DOHME (US) | 2013-02-13 | — | — | EP | disclosed |
| US-7863465-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2011-01-04 | — | — | US | disclosed |
| EP-2007396-A1 | ANTIFUNGAL AGENTS | Merck and Co., Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20080009504-A1 | Antifungal agents | SCYNEXIS, INC. | 2008-01-10 | — | — | US | disclosed |
| WO-2007127012-A1 | ANTIFUNGAL AGENTS | MERCK & CO., INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-4970238-A | Adrenergic blocking agents, cardiovascular disorders | Louis, John William (AU) | 1990-11-13 | — | — | US | disclosed |
| US-4816604-A | CARDIOVASCULAR DISORDERS | Louis, William J. (AU) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009504-A1 | Antifungal agents | DPM1, MAN2B1, MAN2A1 | TDP1 1006/4885L3MBTL1 3320/4885IDO1 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.