Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611788 | 0.76 | MEN1 (0.47) | CA2CA1CA12CA9PKM | |
| SCHEMBL27337126 | 0.76 | CA2 (0.56) | LMNACA2CA1CA12CA9 | |
| SCHEMBL27985930 | 0.76 | LMNA (0.52) | LMNACA2CA1CA12CA9 | |
| SCHEMBL11517135 | 0.76 | LMNA (0.52) | LMNACA2CA1CA12CA9 | |
| SCHEMBL8203443 | 0.76 | ENPP2 (0.56) | LMNACA2CA1CA12CA9 | |
| SCHEMBL15015034 | 0.76 | CA2 (0.50) | LMNACA2CA1CA12CA9 | |
| SCHEMBL29164156 | 0.76 | LMNA (0.52) | LMNACA2CA1CA12CA9 | |
| SCHEMBL2463077 | 0.76 | GAA (0.54) | LMNACA2CA1CA12CA9 | |
| SCHEMBL21449762 | 0.75 | HTR6 (0.50) | CA2CA1CA12CA9CA7 | |
| SCHEMBL872834 | 0.74 | MEN1 (0.56) | LMNACA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9283402-B2 | Apparatus and method for providing a double balloon breast brachytherapy device | BEST MEDICAL INTERNATIONAL, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20120172651-A1 | Apparatus and Method for providing a Double Balloon Breast Brachytherapy Device | Best Medical International, Inc (US) | 2012-07-05 | — | — | US | disclosed |
| CN-1901970-A | Brachytherapy device and method for treating target tissue through external surface | CYTYC CORP (US) | 2007-01-24 | — | — | CN | disclosed |