Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL275817 | 0.91 | MAOA (0.52) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL7863457 | 0.88 | MAOA (0.54) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL8108367 | 0.88 | MAOA (0.54) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL25291666 | 0.84 | MAOA (0.50) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL3139239 | 0.83 | MAOA (0.59) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL27803639 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL28135016 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL27830018 | 0.81 | MAOA (0.58) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL27641511 | 0.81 | MAOA (0.58) | NPC1RAB9AMAOAALDH1A1KDM4E | |
| Fluorene SCHEMBL23706341 | 0.81 | SRD5A2 (0.44) | NPC1RAB9AMAOAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8854730-B2 | Negatively birefringent polyesters and optical films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | PUF60, PARG, PARN | NPC1 3803/4885RAB9A 1662/4885MAOA 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.