Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013480 | 0.92 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL10013483 | 0.89 | HSD17B1 (0.42) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10013473 | 0.89 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL10013452 | 0.85 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL15090468 | 0.84 | HSD17B1 (0.50) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10013477 | 0.84 | HSD17B1 (0.56) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL13142444 | 0.83 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL13142445 | 0.83 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10013484 | 0.83 | HSD17B1 (0.45) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10013468 | 0.83 | PGR (0.41) | HSD17B1HSD17B2CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20080087884-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR | CANON KABUSHIKI KAISHA (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20080087884-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR | CANON KABUSHIKI KAISHA (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080087884-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR | SLC19A2, TCP1, TTI1 | HSD17B1 1220/4885HSD17B2 2253/4885CYP3A4 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.