SCHEMBL1001435

SCHEMBL1001435

C=COC(=O)c1ccccc1N(C)C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
TP53 P04637 1/20 0.56
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
KMT2A Q03164 1/20 0.44
CNR2 P34972 2/20 0.41
CYP3A4 P08684 1/20 0.40
PTPN1 P18031 2/20 0.39
HSD17B10 Q99714 2/20 0.35
BRD4 O60885 1/20 0.35
LMNA P02545 2/20 0.34
RASGRP3 Q8IV61 2/20 0.34
CFTR P13569 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15175 0.81 CYP3A4 (0.55) TSHRALDH1A1TP53CYP3A4HSD17B10
SCHEMBL27426622 0.81 ALDH1A1 (0.50) TSHRALDH1A1GAATP53MAPT
SCHEMBL10367206 0.80 MAPT (0.62) TSHRALDH1A1GAATP53MAPT
SCHEMBL9550019 0.80 TSHR (0.67) TSHRALDH1A1GAATP53MAPT
Ethylene SCHEMBL29113890 0.79 CYP3A4 (0.53) TSHRALDH1A1TP53CYP3A4HSD17B10
SCHEMBL1661184 0.79 CYP3A4 (0.70) TSHRALDH1A1GAATP53MAPT
SCHEMBL43644 0.78 KMT2A (0.67) TSHRALDH1A1GAATP53MAPT
SCHEMBL29408467 0.78 KMT2A (0.67) TSHRALDH1A1GAATP53MAPT
Acetic Acid SCHEMBL27451410 0.78 CYP3A4 (0.48) TSHRALDH1A1TP53CYP3A4HSD17B10
SCHEMBL182408 0.77 NPC1 (0.46) TSHRALDH1A1TP53MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286491-B2 Image forming device and image forming method RICOH COMPANY, LTD. (JP) 2025-04-29 US disclosed
EP-4239000-A1 COMPOSITION FOR FORMING LOW DIELECTRIC CONSTANT RESIN, LOW DIELECTRIC MEMBER, AND ELECTRONIC DEVICE USING SAME JNC Corporation (JP) 2023-09-06 EP disclosed
CN-112175633-B Liquid crystal aligning agent, liquid crystal alignment film, phase difference film, substrate for liquid crystal display element, and liquid crystal display element 捷恩智株式会社 2023-08-01 CN disclosed
CN-115989248-A Composition for forming low dielectric constant resin, low dielectric member, and electronic device using the low dielectric member 捷恩智株式会社 2023-04-18 CN disclosed
CN-115850580-A Composition for forming low dielectric constant resin and use thereof 捷恩智株式会社 2023-03-28 CN disclosed
US-20220259338-A1 IMAGE FORMING DEVICE AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2022-08-18 US disclosed
CN-107794056-B Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystal polymer, retardation film, and display element 捷恩智株式会社 2022-07-05 CN disclosed
CN-109563408-B Polymerizable liquid crystal composition, liquid crystal polymer, retardation film, polarizing plate, display element, and polymerizable liquid crystal compound 捷恩智株式会社 2022-04-19 CN disclosed
US-10961455-B2 Polymerizable liquid crystal composition and liquid crystal polymer JNC CORPORATION (JP) 2021-03-30 US disclosed
US-10844283-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition and liquid crystal polymerized film JNC CORPORATION (JP) 2020-11-24 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-20050007541-A1 Liquid crystalline compound, liquid crystal composition and their polymers JNC PETROCHEMICAL CORPORATION (JP) 2005-01-13 US disclosed
US-6824709-B2 A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2004-11-30 US disclosed
US-20040222403-A1 Polymerizable compounds and their polymers JNC PETROCHEMICAL CORPORATION (JP) 2004-11-11 US disclosed
US-20030203128-A1 Fluorene derivatives and their polymers JNC PETROCHEMICAL CORPORATION (JP) 2003-10-30 US disclosed
US-20020190818-A1 High frequency band pass filter TDK CORPORATION (JP) 2002-12-19 US disclosed
EP-0788118-B1 Low dielectric polymer and film, substrate and electronic part using the same TDK CORP (JP) 2002-11-20 EP disclosed
US-6143850-A COPOLYMER WITH UNITS BASED ON BENZOIC ACID DERIVATIVE CHROMOPHORE-BEARING VINYL ESTERS; GOOD WATER RESISTANCE; LOW SKIN PENETRATION; FOR USE IN COSMETICS BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
US-5914283-A FUMARIC ACID DIESTER MONOMER-CONTAINING POLYMER FILM; HEAT RESISTANCE, WEATHER RESISTANCE TDK CORPORATION (JP) 1999-06-22 US disclosed
EP-0788118-A1 Low dielectric polymer and film, substrate and electronic part using the same TDK Corporation (JP) 1997-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844283-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition and liquid crystal polymerized film NAP1L1, CCNA1, CCNT1 TSHR 4759/4885ALDH1A1 1548/4885GAA 4822/4885
US-10961455-B2 Polymerizable liquid crystal composition and liquid crystal polymer OCIAD2, OCIAD1, CCNT1 TSHR 4605/4885ALDH1A1 1814/4885GAA 4841/4885
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 TSHR 4554/4885ALDH1A1 1780/4885GAA 3979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.