SCHEMBL10014577

SCHEMBL10014577

c1ccc2c(c1)sc1c2ccc2c3ccccc3n(-c3ccc(-c4ccc(-n5c6ccccc6c6ccc7c8ccccc8sc7c65)cc4)cc3)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 1/20 0.38
GPR3 P46089 1/20 0.37
TP53 P04637 4/20 0.36
HDAC4 P56524 1/20 0.35
HSD17B10 Q99714 1/20 0.34
RXFP1 Q9HBX9 2/20 0.33
MAPT P10636 6/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24923497 1.00 ATM (0.41) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL22710508 0.99 ATM (0.43) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL24173611 0.99 ATM (0.43) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL10014563 0.97 L3MBTL1 (0.42) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL10014576 0.95 ATM (0.44) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL17246454 0.94 ATM (0.47) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL17246456 0.93 L3MBTL1 (0.39) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL17246462 0.93 MAPT (0.38) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL24923488 0.92 ALOX5 (0.47) ATMKDM4EL3MBTL1ALOX5GPR3
SCHEMBL24676125 0.92 KDM4E (0.38) ATMKDM4EL3MBTL1ALOX5GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20220238815-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2022-07-28 US disclosed
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUK SAN NEOLUX CO., LTD. (KR) 2021-04-27 US disclosed
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-20150053960-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME DUK SAN NEOLUX CO., LTD. (KR) 2015-02-26 US disclosed
US-20150053960-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME DUK SAN NEOLUX CO., LTD. (KR) 2015-02-26 US disclosed
US-8889271-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUKSAN HIGH METAL CO., LTD. (KR) 2014-11-18 US disclosed
US-8889271-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUKSAN HIGH METAL CO., LTD. (KR) 2014-11-18 US disclosed
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same NOTUM, OR10J3, PER2 ATM 3651/4885KDM4E 1424/4885L3MBTL1 2162/4885
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A ATM 2806/4885KDM4E 3096/4885L3MBTL1 173/4885
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same NOTUM, OR10J3, PER2 ATM 3651/4885KDM4E 1424/4885L3MBTL1 2162/4885
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME NOTUM, OR10J3, PER2 ATM 3651/4885KDM4E 1424/4885L3MBTL1 2162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.