Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014726 | 0.93 | KMT2A (0.54) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL14537561 | 0.88 | LMNA (0.51) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL17637042 | 0.77 | NPSR1 (0.55) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL801366 | 0.76 | HTT (0.60) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL13943151 | 0.74 | HTT (0.47) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL11508035 | 0.73 | LMNA (0.55) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL17637037 | 0.72 | KMT2A (0.61) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL11964790 | 0.71 | HTT (0.67) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL15255520 | 0.71 | HTT (0.56) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL12267193 | 0.70 | HTT (0.58) | MEN1KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009371-A1 | INTERMEDIATE TRANSFER MEMBER | XEROX CORPORATION (US) | 2012-01-12 | — | — | US | disclosed |