Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637038 | 0.85 | POLB (0.40) | NPSR1POLBKDM4EMAPK1TDP1 | |
| SCHEMBL10014726 | 0.83 | KMT2A (0.54) | KDM4EALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL18120597 | 0.82 | KDM4E (0.71) | NPSR1POLBKDM4EMAPK1TDP1 | |
| SCHEMBL14537561 | 0.78 | LMNA (0.51) | KDM4EALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL10014727 | 0.77 | MEN1 (0.50) | KDM4ETDP1ALDH1A1HTTKMT2A | |
| SCHEMBL17637037 | 0.75 | KMT2A (0.61) | NPSR1KDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL6931910 | 0.72 | MAPK1 (0.69) | NPSR1POLBKDM4EMAPK1TDP1 | |
| SCHEMBL13863485 | 0.71 | AR (0.48) | KDM4ETDP1ALDH1A1HTTKMT2A | |
| SCHEMBL13299368 | 0.71 | ABCB1 (0.67) | NPSR1POLBKDM4EMAPK1TDP1 | |
| SCHEMBL22104295 | 0.70 | HTT (0.59) | POLBKDM4EMAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040896-B2 | Silane functionalized compounds and compositions thereof | Hexion, Inc. (US) | 2018-08-07 | — | — | US | disclosed |
| US-10040896-B2 | Silane functionalized compounds and compositions thereof | Hexion, Inc. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-03-31 | — | — | US | disclosed |
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090439-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | ILK, CAD, CAPG | NPSR1 982/4885POLB 3996/4885KDM4E 1221/4885 |
| US-10040896-B2 | Silane functionalized compounds and compositions thereof | ILK, CAD, CAPG | NPSR1 982/4885POLB 3996/4885KDM4E 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.